Literature DB >> 22955719

[Basic principles of therapy with neuropsychotropic drugs].

G Gründer1, T Veselinović, M Paulzen.   

Abstract

This review provides the general principles for a rational therapy with psychotropic drugs. It covers the discussion on the basics of the pharmacokinetics (with consideration of drug metabolism and the importance of genetic polymorphisms), pharmacodynamics (drug-receptor interaction, receptor pharmacology) and the effects of chronic administration of neuropsychotropic drugs on behavior. The reader will thus obtain the basis and stimulation for further study.

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Year:  2012        PMID： 22955719     DOI： 10.1007/s00115-012-3554-1

Source DB:  PubMed          Journal:  Nervenarzt        ISSN： 0028-2804            Impact factor:   1.214


  8 in total

1.  Cytochrome P450 2D6 polymorphism and its impact on decision-making in psychopharmacotherapy: finding the right way in an ultrarapid metabolizing patient.

Authors:  Michael Paulzen; Simone C Tauber; André Kirner-Veselinovic; Gerhard Gründer
Journal:  J Clin Psychiatry       Date:  2011-11       Impact factor: 4.384

2.  Drug interaction can lead to undetectable serum concentrations of quetiapine in the presence of carbamazepine.

Authors:  Thomas Nickl-Jockschat; Michael Paulzen; Frank Schneider; Michael Grözinger
Journal:  Clin Neuropharmacol       Date:  2009 Jan-Feb       Impact factor: 1.592

3.  [Expanding therapeutic reference ranges using dose-related reference ranges].

Authors:  E Haen; C Greiner; W Bader; M Wittmann
Journal:  Nervenarzt       Date:  2008-05       Impact factor: 1.214

4.  Genetic mechanisms for duplication and multiduplication of the human CYP2D6 gene and methods for detection of duplicated CYP2D6 genes.

Authors:  E Lundqvist; I Johansson; M Ingelman-Sundberg
Journal:  Gene       Date:  1999-01-21       Impact factor: 3.688

5.  Modeling sensitization to stimulants in humans: an [11C]raclopride/positron emission tomography study in healthy men.

Authors:  Isabelle Boileau; Alain Dagher; Marco Leyton; Roger N Gunn; Glen B Baker; Mirko Diksic; Chawki Benkelfat
Journal:  Arch Gen Psychiatry       Date:  2006-12

6.  AGNP Consensus Guidelines for Therapeutic Drug Monitoring in Psychiatry: Update 2011.

Authors:  C Hiemke; P Baumann; N Bergemann; A Conca; O Dietmaier; K Egberts; M Fric; M Gerlach; C Greiner; G Gründer; E Haen; U Havemann-Reinecke; E Jaquenoud Sirot; H Kirchherr; G Laux; U C Lutz; T Messer; M J Müller; B Pfuhlmann; B Rambeck; P Riederer; B Schoppek; J Stingl; M Uhr; S Ulrich; R Waschgler; G Zernig
Journal:  Pharmacopsychiatry       Date:  2011-09-27       Impact factor: 5.788

7.  D2-receptor upregulation is dependent upon temporal course of D2-occupancy: a longitudinal [11C]-raclopride PET study in cats.

Authors:  Nathalie Ginovart; Alan A Wilson; Doug Hussey; Sylvain Houle; Shitij Kapur
Journal:  Neuropsychopharmacology       Date:  2008-08-06       Impact factor: 7.853

8.  Conditioned dopamine release in humans: a positron emission tomography [11C]raclopride study with amphetamine.

Authors:  Isabelle Boileau; Alain Dagher; Marco Leyton; Krzysztof Welfeld; Linda Booij; Mirko Diksic; Chawki Benkelfat
Journal:  J Neurosci       Date:  2007-04-11       Impact factor: 6.167
  8 in total
  1 in total

Review 1.  [Therapeutic drug monitoring in psychiatry. A brief summary of the new consensus paper by the task force on TDM of the AGNP].

Authors:  G Gründer; P Baumann; A Conca; G Zernig; C Hiemke
Journal:  Nervenarzt       Date:  2014-07       Impact factor: 1.214
  1 in total

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