BACKGROUND: Motor impairment and travel time have been shown to be important barriers to recruitment for Parkinson's disease (PD) clinical trials. This study determined whether use of Internet-based video communication for study visits would improve likelihood of participating in PD clinical trials. SUBJECTS AND METHODS: University of Utah PD clinic patients were invited to complete a survey asking if they would be willing to participate in a hypothetical research study under four different scenarios. McNemar's test was used to test the hypothesis that remote assessments would improve willingness to participate. RESULTS: Willingness to participate was 101/113 (87%) in the standard scenario. Willingness to participate was highest (93%; p=0.046) with most visits occurring via telemedicine at a local clinic, followed by some visits occurring via telemedicine at a local clinic (91%; p=0.157). Willingness to participate was lower with some (80%; p=0.008) or most (82%; p=0.071) visits occurring by home telemonitoring. CONCLUSIONS: Use of telemedicine may be an acceptable means to improve participation in clinical trials. This would need to be confirmed with the use of a larger-scale inquiry involving rural populations. Future research should assess subject or caregiver comfort and trainability with respect to computer-based technology in the home and systems barriers for wider implementation of telemedicine in neurology.
BACKGROUND:Motor impairment and travel time have been shown to be important barriers to recruitment for Parkinson's disease (PD) clinical trials. This study determined whether use of Internet-based video communication for study visits would improve likelihood of participating in PD clinical trials. SUBJECTS AND METHODS: University of Utah PD clinic patients were invited to complete a survey asking if they would be willing to participate in a hypothetical research study under four different scenarios. McNemar's test was used to test the hypothesis that remote assessments would improve willingness to participate. RESULTS: Willingness to participate was 101/113 (87%) in the standard scenario. Willingness to participate was highest (93%; p=0.046) with most visits occurring via telemedicine at a local clinic, followed by some visits occurring via telemedicine at a local clinic (91%; p=0.157). Willingness to participate was lower with some (80%; p=0.008) or most (82%; p=0.071) visits occurring by home telemonitoring. CONCLUSIONS: Use of telemedicine may be an acceptable means to improve participation in clinical trials. This would need to be confirmed with the use of a larger-scale inquiry involving rural populations. Future research should assess subject or caregiver comfort and trainability with respect to computer-based technology in the home and systems barriers for wider implementation of telemedicine in neurology.
Authors: E Ray Dorsey; Lisa M Deuel; Tiffini S Voss; Kara Finnigan; Benjamin P George; Sheelah Eason; David Miller; Jason I Reminick; Anna Appler; Joyce Polanowicz; Lucy Viti; Sandy Smith; Anthony Joseph; Kevin M Biglan Journal: Mov Disord Date: 2010-08-15 Impact factor: 10.338
Authors: E Ray Dorsey; Tiffini S Voss; David R Shprecher; Lisa M Deuel; Christopher A Beck; Irenita F Gardiner; Margaret A Coles; Richard S Burns; Frederick J Marshall; Kevin M Biglan Journal: Mov Disord Date: 2010-10-15 Impact factor: 10.338
Authors: Martijn van der Eijk; Marjan J Faber; Johanna W M Aarts; Jan A M Kremer; Marten Munneke; Bastiaan R Bloem Journal: J Med Internet Res Date: 2013-06-25 Impact factor: 5.428
Authors: Taylor L Myers; Erika F Augustine; Elizabeth Baloga; Margaret Daeschler; Paul Cannon; Helen Rowbotham; Eli Chanoff; Stella Jensen-Roberts; Julia Soto; Robert G Holloway; Connie Marras; Caroline M Tanner; E Ray Dorsey; Ruth B Schneider Journal: J Parkinsons Dis Date: 2022 Impact factor: 5.568