Literature DB >> 2295325

Ascaris lumbricoides: detecting its metabolites in the urine of infected people using gas-liquid chromatography.

A Hall1, T Romanova.   

Abstract

Substances dissolved in the urine of people infected with Ascaris lumbricoides were extracted and detected by gas-liquid chromatography. The ratios of the areas of the peaks produced by two substances extracted from urine to the area of the peak of solvent were found to be significantly correlated with the worm burden. A chemical analysis of the predominant substance by infrared spectrophotometry and proton magnetic resonance spectrometry indicated that it was 2-methyl-butyramide. The chemical properties of the other substance indicated that it was 2-methyl-valeramide. These substances are likely to be derivatives of two acids known to be end products of the carbohydrate metabolism of Ascaris.

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Year:  1990        PMID： 2295325     DOI： 10.1016/0014-4894(90)90083-o

Source DB:  PubMed          Journal:  Exp Parasitol        ISSN： 0014-4894            Impact factor:   2.011


  6 in total

1.  Metabolomic profiling of the excretory-secretory products of hookworm and whipworm.

Authors:  Phurpa Wangchuk; Konstantinos Kouremenos; Ramon M Eichenberger; Mark Pearson; Atik Susianto; David S Wishart; Malcolm J McConville; Alex Loukas
Journal:  Metabolomics       Date:  2019-06-28       Impact factor: 4.290

Review 2.  A review and meta-analysis of the impact of intestinal worms on child growth and nutrition.

Authors:  Andrew Hall; Gillian Hewitt; Veronica Tuffrey; Nilanthi de Silva
Journal:  Matern Child Nutr       Date:  2008-04       Impact factor: 3.092

3.  2-methyl butyramide, a previously identified urine biomarker for Ascaris lumbricoides, is not present in infected Indonesian individuals.

Authors:  Ole Lagatie; Emmanuel Njumbe Ediage; Jeroen A Pikkemaat; Yenny Djuardi; Lieven J Stuyver
Journal:  Parasit Vectors       Date:  2017-12-29       Impact factor: 3.876

Review 4.  Human Ascariasis: Diagnostics Update.

Authors:  Poppy H L Lamberton; Peter M Jourdan
Journal:  Curr Trop Med Rep       Date:  2015-10-03

Review 5.  An update on non-invasive urine diagnostics for human-infecting parasitic helminths: what more could be done and how?

Authors:  John Archer; James E LaCourse; Bonnie L Webster; J Russell Stothard
Journal:  Parasitology       Date:  2019-12-13       Impact factor: 3.234

6.  2-Methyl-pentanoyl-carnitine (2-MPC): a urine biomarker for patent Ascaris lumbricoides infection.

Authors:  Ole Lagatie; Ann Verheyen; Stijn Van Asten; Maurice R Odiere; Yenny Djuardi; Bruno Levecke; Johnny Vlaminck; Zeleke Mekonnen; Daniel Dana; Ruben T'Kindt; Koen Sandra; Rianne van Outersterp; Jos Oomens; Ronghui Lin; Lieve Dillen; Rob Vreeken; Filip Cuyckens; Lieven J Stuyver
Journal:  Sci Rep       Date:  2020-09-25       Impact factor: 4.379
  6 in total

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