| Literature DB >> 2295117 |
Abstract
Oral idarubicin (40 mg/m2 in 3-4 divided doses over 24 h every 21 days) was tested in a group of patients with drug-resistant ovarian carcinoma. None of 13 patients responded and the study was discontinued. Toxicity was acceptable, with neutropaenia being dose-limiting. It seems unlikely that idarubicin has significant activity in this disease although phase II studies should ideally be conducted in less heavily pretreated patients.Entities:
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Year: 1990 PMID： 2295117 DOI： 10.1007/bf00684891
Source DB: PubMed Journal: Cancer Chemother Pharmacol ISSN： 0344-5704 Impact factor: 3.333