Literature DB >> 22948998

Vitamin B₁₂ deficiency: an unusual cause for recurrent generalised seizures with pancytopaenia.

Kushal Naha1, Sowjanya Dasari, G Vivek, Mukhyaprana Prabhu.   

Abstract

We report the case of a 70-year-old man with pancytopaenia and new-onset recurrent generalised seizures. Detailed evaluation yielded a diagnosis of vitamin B(12) deficiency. He was treated with parenteral vitamin B(12) supplementation and antiepileptic drugs. Seizures are an unusual manifestation of vitamin B(12) deficiency and possible mechanisms of epileptogenesis are discussed.

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Year:  2012        PMID： 22948998      PMCID： PMC4543758          DOI： 10.1136/bcr-2012-006632

Source DB:  PubMed          Journal:  BMJ Case Rep        ISSN： 1757-790X


  14 in total

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Authors:  Meng Lee; Hong-Shiu Chang; Hsiao-Ting Wu; Hsu-Huei Weng; Chiung-Mei Chen
Journal:  Epilepsia       Date:  2005-07       Impact factor: 5.864

2.  Neurologic aspects of cobalamin deficiency.

Authors:  E B Healton; D G Savage; J C Brust; T J Garrett; J Lindenbaum
Journal:  Medicine (Baltimore)       Date:  1991-07       Impact factor: 1.889

3.  Convulsant action of D,L-homocysteic acid and its stereoisomers in immature rats.

Authors:  P Mares; J Folbergrová; M Langmeier; R Haugvicová; H Kubová
Journal:  Epilepsia       Date:  1997-07       Impact factor: 5.864

4.  Facilitatory and direct excitatory effects of folate and folinate on single neurones of cat cerebral cortex.

Authors:  J Davies; J C Watkins
Journal:  Biochem Pharmacol       Date:  1973-07-01       Impact factor: 5.858

5.  Epileptogenic activity of sodium-folate and the blood-brain barrier in the rat.

Authors:  O R Hommes; E A Obbens; C C Wijffels
Journal:  J Neurol Sci       Date:  1973-05       Impact factor: 3.181

Review 6.  Vitamin B12, folic acid, and the nervous system.

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Journal:  Lancet Neurol       Date:  2006-11       Impact factor: 44.182

Review 7.  Folate, vitamin B12 and vitamin B6 and one carbon metabolism.

Authors:  J Selhub
Journal:  J Nutr Health Aging       Date:  2002       Impact factor: 4.075

Review 8.  Epilepsy and multiple sclerosis.

Authors:  Charles M Poser; Vesna V Brinar
Journal:  Epilepsy Behav       Date:  2003-02       Impact factor: 2.937

9.  Antiepileptic drugs interact with folate and vitamin B12 serum levels.

Authors:  Michael Linnebank; Susanna Moskau; Alexander Semmler; Guido Widman; Birgit Stoffel-Wagner; Michael Weller; Christian E Elger
Journal:  Ann Neurol       Date:  2011-01-19       Impact factor: 10.422

10.  Early-onset cobalamin C/D deficiency: epilepsy and electroencephalographic features.

Authors:  Roberta Biancheri; Roberto Cerone; Andrea Rossi; Maria Cristina Schiaffino; Ubaldo Caruso; Giuseppe Minniti; Maria Viviana Perrone; Paolo Tortori-Donati; Edvige Veneselli
Journal:  Epilepsia       Date:  2002-06       Impact factor: 5.864
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  6 in total

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Journal:  Am J Case Rep       Date:  2015-06-23

2.  Association of vitamin B12 deficiency and metformin use in patients with type 2 diabetes.

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Journal:  J Korean Med Sci       Date:  2014-07-11       Impact factor: 2.153

3.  Higher prevalence of metformin-induced vitamin B12 deficiency in sulfonylurea combination compared with insulin combination in patients with type 2 diabetes: a cross-sectional study.

Authors:  Donghoon Kang; Jae-Seung Yun; Sun-Hye Ko; Tae-Seok Lim; Yu-Bae Ahn; Yong-Moon Park; Seung-Hyun Ko
Journal:  PLoS One       Date:  2014-10-09       Impact factor: 3.240

4.  VITAMIN B12 LEVELS IN PATIENTS WITH TYPE 2 DIABETES MELLITUS ON METFORMIN.

Authors:  K S Akinlade; S O Agbebaku; S K Rahamon; W O Balogun
Journal:  Ann Ib Postgrad Med       Date:  2015-12

5.  Prevalence of Vitamin B12 Deficiency and its Associated Factors among Patients with Type 2 Diabetes Mellitus on Metformin from a District in Malaysia.

Authors:  Gayathri Devi Krishnan; Miza Hiryanti Zakaria; Norhayati Yahaya
Journal:  J ASEAN Fed Endocr Soc       Date:  2020-08-25

6.  Metformin treatment in young children with fragile X syndrome.

Authors:  Hazel Maridith B Biag; Laura A Potter; Victoria Wilkins; Sumra Afzal; Alexis Rosvall; Maria Jimena Salcedo-Arellano; Akash Rajaratnam; Ramiro Manzano-Nunez; Andrea Schneider; Flora Tassone; Susan M Rivera; Randi J Hagerman
Journal:  Mol Genet Genomic Med       Date:  2019-09-14       Impact factor: 2.183
  6 in total

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