Literature DB >> 22948345

[Spontaneous hematoma and hip pain in a 65-year old patient].

C Sucker1, S Korfmacher, M Papp-Váry, C Grieser, H Riess.   

Abstract

The case of a 65-year-old woman with acquired hemophilia is reported. Acquired hemophilia is characterized by the development of inhibitors directed against coagulation factors. Impairment of plasmatic hemostasis leads to a severe bleeding tendency in individuals without a preexisting coagulation defect with considerable mortality. Pathophysiology, diagnostic work-up, and treatment are summarized and discussed.

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Mesh：

Year:  2012        PMID： 22948345     DOI： 10.1007/s00108-012-3105-7

Source DB:  PubMed          Journal:  Internist (Berl)        ISSN： 0020-9554            Impact factor:   0.743


  8 in total

1.  Immunological characterization of factor VIII autoantibodies in patients with acquired hemophilia A in the presence or absence of underlying disease.

Authors:  T Matsumoto; M Shima; K Fukuda; K Nogami; J C Giddings; T Murakami; I Tanaka; A Yoshioka
Journal:  Thromb Res       Date:  2001-12-15       Impact factor: 3.944

2.  Induction of tolerance after combined immunosuppression and -adsorption in two patients with acquired haemophilia after severe haemorrhages controlled by sequential administration of rFVIIa and FEIBA.

Authors:  Marcus Stockschläder; Leilani Ruf; Anne Linderer; Thomas Schroeder; Wolfram T Knoefel; Rainer Haas; Günther Giers; Andrea Gerhardt; Christoph Sucker; Rainer B Zotz; Rüdiger E Scharf
Journal:  Thromb Haemost       Date:  2009-03       Impact factor: 5.249

3.  Activated prothrombin complex concentrate for acquired haemophilia when recombinant factor VIIa fails.

Authors:  Z Hussein; G C Kudva; H J Reimers
Journal:  Haemophilia       Date:  2009-01-20       Impact factor: 4.287

Review 4.  Acquired hemophilia A.

Authors:  Massimo Franchini; Giuseppe Lippi
Journal:  Adv Clin Chem       Date:  2011       Impact factor: 5.394

5.  The Nijmegen modification of the Bethesda assay for factor VIII:C inhibitors: improved specificity and reliability.

Authors:  B Verbruggen; I Novakova; H Wessels; J Boezeman; M van den Berg; E Mauser-Bunschoten
Journal:  Thromb Haemost       Date:  1995-02       Impact factor: 5.249

Review 6.  Acquired hemophilia a: diagnosis, aetiology, clinical spectrum and treatment options.

Authors:  Shrimati Shetty; Manali Bhave; Kanjaksha Ghosh
Journal:  Autoimmun Rev       Date:  2010-11-27       Impact factor: 9.754

Review 7.  A cell-based model of thrombin generation.

Authors:  Harold R Roberts; Maureane Hoffman; Dougald M Monroe
Journal:  Semin Thromb Hemost       Date:  2006-04       Impact factor: 4.180

Review 8.  Management of acquired haemophilia A.

Authors:  P W Collins
Journal:  J Thromb Haemost       Date:  2011-07       Impact factor: 5.824
  8 in total

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