Literature DB >> 22946720

Traumatic brain injury: risks of epilepsy and implications for medicolegal assessment.

Jakob Christensen1.   

Abstract

Traumatic brain injury (TBI) is a potentially preventable cause of epilepsy. Increasing incidence among army personnel and the high incidence among children and young people raise concern. This article presents a review of selected studies dealing with the risks of TBI and the risk of posttraumatic epilepsy in humans. The incidence of persons admitted to hospital with TBI has decreased in developed countries in recent years. However, there is little change in TBI-associated deaths, and the decrease in hospitalization may merely reflect that more people with head injury are cared for on an outpatient basis. It is clear that epilepsy is a frequent consequence of brain injury, even many years after the injury. However, several well-controlled studies have been unable to identify therapies that prevent the development of epilepsy after TBI. Posttraumatic epilepsy has significant implications for the affected individuals, family, and society. Despite several interventions used to prevent posttraumatic epilepsy, the only proven "intervention" to date is to prevent TBI from occurring. Wiley Periodicals, Inc.
© 2012 International League Against Epilepsy.

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Year:  2012        PMID: 22946720     DOI: 10.1111/j.1528-1167.2012.03612.x

Source DB:  PubMed          Journal:  Epilepsia        ISSN: 0013-9580            Impact factor:   5.864


  11 in total

1.  Distinct effect of impact rise times on immediate and early neuropathology after brain injury in juvenile rats.

Authors:  Eric J Neuberger; Radia Abdul Wahab; Archana Jayakumar; Bryan J Pfister; Vijayalakshmi Santhakumar
Journal:  J Neurosci Res       Date:  2014-05-05       Impact factor: 4.164

2.  α-Helical protein absorption at post-traumatic epileptic foci monitored by Fourier transform infrared mapping.

Authors:  Siyang Xiang; Dong Zhao; Hongxia Hao; X U Wang; Ling Li; Tiantong Yang
Journal:  J Biosci       Date:  2020       Impact factor: 1.826

Review 3.  Breakdown of blood brain barrier as a mechanism of post-traumatic epilepsy.

Authors:  Aaron Dadas; Damir Janigro
Journal:  Neurobiol Dis       Date:  2018-07-18       Impact factor: 5.996

4.  Acute seizures predict epilepsy after childhood stroke.

Authors:  Christine K Fox; Hannah C Glass; Stephen Sidney; Daniel H Lowenstein; Heather J Fullerton
Journal:  Ann Neurol       Date:  2013-08       Impact factor: 10.422

Review 5.  Novel frontiers in epilepsy treatments: preventing epileptogenesis by targeting inflammation.

Authors:  Raimondo D'Ambrosio; Clifford L Eastman; Cinzia Fattore; Emilio Perucca
Journal:  Expert Rev Neurother       Date:  2013-06       Impact factor: 4.618

Review 6.  In vivo models of cortical acquired epilepsy.

Authors:  Sylvain Chauvette; Sara Soltani; Josée Seigneur; Igor Timofeev
Journal:  J Neurosci Methods       Date:  2015-09-03       Impact factor: 2.390

7.  Repetitive Diffuse Mild Traumatic Brain Injury Causes an Atypical Astrocyte Response and Spontaneous Recurrent Seizures.

Authors:  Oleksii Shandra; Alexander R Winemiller; Benjamin P Heithoff; Carmen Munoz-Ballester; Kijana K George; Michael J Benko; Ivan A Zuidhoek; Michelle N Besser; Dallece E Curley; G Franklin Edwards; Anroux Mey; Alexys N Harrington; Jeremy P Kitchen; Stefanie Robel
Journal:  J Neurosci       Date:  2019-01-21       Impact factor: 6.167

8.  Brainstem and Cortical Spreading Depolarization in a Closed Head Injury Rat Model.

Authors:  Refat Aboghazleh; Ellen Parker; Lynn T Yang; Daniela Kaufer; Jens P Dreier; Alon Friedman; Gerben van Hameren
Journal:  Int J Mol Sci       Date:  2021-10-28       Impact factor: 5.923

Review 9.  Role of Anticonvulsants in the Management of Posttraumatic Epilepsy.

Authors:  Batool F Kirmani; Diana Mungall Robinson; Ekokobe Fonkem; Kevin Graf; Jason H Huang
Journal:  Front Neurol       Date:  2016-03-22       Impact factor: 4.003

10.  Pharmacological management of post-traumatic seizures in adults: current practice patterns in the UK and the Republic of Ireland.

Authors:  Harry Mee; Angelos G Kolias; Aswin Chari; Ari Ercole; Fiona Lecky; Carole Turner; Catrin Tudur-Smith; Jonathan Coles; Fahim Anwar; Antonio Belli; Mark Manford; Timothy Ham; Catherine McMahon; Diederik Bulters; Chris Uff; John S Duncan; Mark H Wilson; Anthony G Marson; Peter J Hutchinson
Journal:  Acta Neurochir (Wien)       Date:  2018-10-01       Impact factor: 2.216

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