BACKGROUND: Little is known about the etiology of pancreatic cancer. Epidemiological studies on tea consumption and pancreatic cancer risk have been inconclusive. The purpose of the present study was to investigate the association between green tea drinking and the risk of pancreatic cancer in urban Shanghai, China. METHODS: In this population-based case-control study conducted in urban Shanghai, 908 cases of pancreatic cancer and 1067 healthy controls were recruited. Information on tea drinking, including type of tea, amount of tea consumption, temperature of tea, and the duration of regular tea drinking, were collected via interview questionnaire. RESULTS: We examined the association of multiple tea drinking habits with the risk of pancreatic cancer. In women, regular green tea drinking was associated with 32% reduction of pancreatic cancer risk (OR 0.68, 95% CI 0.48-0.96), compared to those who did not drink tea regularly. Increased consumption and longer duration of tea drinking were both associated with reduced pancreatic cancer risk in women. Among regular tea drinkers, lower temperature of tea was associated with reduced risk of pancreatic cancer in both men and women, independent of amount or duration of tea drinking. CONCLUSIONS: Habits of green tea drinking, including regular drinking, amount of consumption, persistence of the habit, and tea temperature, may lower pancreatic cancer risk.
BACKGROUND: Little is known about the etiology of pancreatic cancer. Epidemiological studies on tea consumption and pancreatic cancer risk have been inconclusive. The purpose of the present study was to investigate the association between green tea drinking and the risk of pancreatic cancer in urban Shanghai, China. METHODS: In this population-based case-control study conducted in urban Shanghai, 908 cases of pancreatic cancer and 1067 healthy controls were recruited. Information on tea drinking, including type of tea, amount of tea consumption, temperature of tea, and the duration of regular tea drinking, were collected via interview questionnaire. RESULTS: We examined the association of multiple tea drinking habits with the risk of pancreatic cancer. In women, regular green tea drinking was associated with 32% reduction of pancreatic cancer risk (OR 0.68, 95% CI 0.48-0.96), compared to those who did not drink tea regularly. Increased consumption and longer duration of tea drinking were both associated with reduced pancreatic cancer risk in women. Among regular tea drinkers, lower temperature of tea was associated with reduced risk of pancreatic cancer in both men and women, independent of amount or duration of tea drinking. CONCLUSIONS: Habits of green tea drinking, including regular drinking, amount of consumption, persistence of the habit, and tea temperature, may lower pancreatic cancer risk.
Authors: Shannon M Lynch; Alina Vrieling; Jay H Lubin; Peter Kraft; Julie B Mendelsohn; Patricia Hartge; Federico Canzian; Emily Steplowski; Alan A Arslan; Myron Gross; Kathy Helzlsouer; Eric J Jacobs; Andrea LaCroix; Gloria Petersen; Wei Zheng; Demetrius Albanes; Laufey Amundadottir; Sheila A Bingham; Paolo Boffetta; Marie-Christine Boutron-Ruault; Stephen J Chanock; Sandra Clipp; Robert N Hoover; Kevin Jacobs; Karen C Johnson; Charles Kooperberg; Juhua Luo; Catherine Messina; Domenico Palli; Alpa V Patel; Elio Riboli; Xiao-Ou Shu; Laudina Rodriguez Suarez; Gilles Thomas; Anne Tjønneland; Geoffrey S Tobias; Elissa Tong; Dimitrios Trichopoulos; Jarmo Virtamo; Weimin Ye; Kai Yu; Anne Zeleniuch-Jacquette; H Bas Bueno-de-Mesquita; Rachael Z Stolzenberg-Solomon Journal: Am J Epidemiol Date: 2009-06-26 Impact factor: 4.897
Authors: B T Ji; W H Chow; A W Hsing; J K McLaughlin; Q Dai; Y T Gao; W J Blot; J F Fraumeni Journal: Int J Cancer Date: 1997-01-27 Impact factor: 7.396
Authors: L J Harnack; K E Anderson; W Zheng; A R Folsom; T A Sellers; L H Kushi Journal: Cancer Epidemiol Biomarkers Prev Date: 1997-12 Impact factor: 4.254