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Literature DB >> 22942103

The genetic factors influencing the development of trichotillomania.

Koushik Chattopadhyay¹, Koushik Chatterjee.

Abstract

Trichotillomania (TTM), an obsessive-compulsive spectrum disorder (OCSD), is a psychiatric condition characterized by repetitive hair pulling. Evidence from family and twin studies suggest a heritable link of TTM. Functional polymorphisms in genes involved in neuronal pathways might influence the susceptibility to TTM. This review is an attempt to compile the genetic factors reported to modify the development of TTM.

Entities: Disease

Mesh：

Substances：

Year: 2012 PMID： 22942103 DOI： 10.1007/s12041-011-0094-6

Source DB: PubMed Journal: J Genet ISSN： 0022-1333 Impact factor: 1.166

37 in total

1. The potential role of haloperidol in the treatment of trichotillomania.

Authors: M Van Ameringen; C Mancini; J M Oakman; P Farvolden
Journal: J Affect Disord Date: 1999-12 Impact factor: 4.839

2. SLITRK1 mutations in trichotillomania.

Authors: S Zuchner; M L Cuccaro; K N Tran-Viet; H Cope; R R Krishnan; M A Pericak-Vance; H H Wright; A Ashley-Koch
Journal: Mol Psychiatry Date: 2006-10 Impact factor: 15.992

3. Assessment of grooming and other behavioural responses to the D-1 dopamine receptor agonist SK & F 38393 and its R- and S-enantiomers in the intact adult rat.

Authors: A G Molloy; J L Waddington
Journal: Psychopharmacology (Berl) Date: 1987 Impact factor: 4.530

4. Prevalence of trichotillomania in a college freshman population.

Authors: B O Rothbaum; L Shaw; R Morris; P T Ninan
Journal: J Clin Psychiatry Date: 1993-02 Impact factor: 4.384

5. A genetic polymorphism in the promoter region of DRD4 associated with expression and schizophrenia.

Authors: Y Okuyama; H Ishiguro; M Toru; T Arinami
Journal: Biochem Biophys Res Commun Date: 1999-05-10 Impact factor: 3.575

6. Association of serotonin 5-HT2A receptor binding and the T102C polymorphism in depressed and healthy Caucasian subjects.

Authors: Vadim D Khait; Yung-yu Huang; Gil Zalsman; Maria A Oquendo; David A Brent; Jill M Harkavy-Friedman; J John Mann
Journal: Neuropsychopharmacology Date: 2005-01 Impact factor: 7.853

7. Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study.

Authors: O J Bienvenu; Y Wang; Y Y Shugart; J M Welch; M A Grados; A J Fyer; S L Rauch; J T McCracken; S A Rasmussen; D L Murphy; B Cullen; D Valle; R Hoehn-Saric; B D Greenberg; A Pinto; J A Knowles; J Piacentini; D L Pauls; K Y Liang; V L Willour; M Riddle; J F Samuels; G Feng; G Nestadt
Journal: Am J Med Genet B Neuropsychiatr Genet Date: 2009-07-05 Impact factor: 3.568

The genetic factors influencing the development of trichotillomania.

1. The potential role of haloperidol in the treatment of trichotillomania.

2. SLITRK1 mutations in trichotillomania.

3. Assessment of grooming and other behavioural responses to the D-1 dopamine receptor agonist SK & F 38393 and its R- and S-enantiomers in the intact adult rat.

4. Prevalence of trichotillomania in a college freshman population.

5. A genetic polymorphism in the promoter region of DRD4 associated with expression and schizophrenia.

6. Association of serotonin 5-HT2A receptor binding and the T102C polymorphism in depressed and healthy Caucasian subjects.

7. Sapap3 and pathological grooming in humans: Results from the OCD collaborative genetics study.

Review 8. Multiple rare SAPAP3 missense variants in trichotillomania and OCD.

9. Trichotillomania. An obsessive compulsive spectrum disorder?

10. Hair pulling (trichotillomania).

1. A patch of hair loss on the scalp.

2. Genetics of OCD and Related Disorders; Searching for Shared Factors.

3. Familial trichotillomania in three generations.

4. Slitrk1 is localized to excitatory synapses and promotes their development.