Literature DB >> 22941774

Physiological role of hepatic NPC1L1 in human cholesterol and lipoprotein metabolism: new perspectives and open questions.

Philip N Howles1, David Y Hui.   

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Year:  2012        PMID： 22941774      PMCID： PMC3465994          DOI： 10.1194/jlr.E031823

Source DB:  PubMed          Journal:  J Lipid Res        ISSN： 0022-2275            Impact factor:   5.922


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  31 in total

1.  Influence of class B scavenger receptors on cholesterol flux across the brush border membrane and intestinal absorption.

Authors:  David V Nguyen; Victor A Drover; Martin Knopfel; Padmaja Dhanasekaran; Helmut Hauser; Michael C Phillips
Journal:  J Lipid Res       Date:  2009-05-19       Impact factor: 5.922

2.  Ezetimibe, a potent cholesterol absorption inhibitor, inhibits the development of atherosclerosis in ApoE knockout mice.

Authors:  H R Davis; D S Compton; L Hoos; G Tetzloff
Journal:  Arterioscler Thromb Vasc Biol       Date:  2001-12       Impact factor: 8.311

3.  The target of ezetimibe is Niemann-Pick C1-Like 1 (NPC1L1).

Authors:  Margarita Garcia-Calvo; JeanMarie Lisnock; Herbert G Bull; Brian E Hawes; Duane A Burnett; Matthew P Braun; James H Crona; Harry R Davis; Dennis C Dean; Patricia A Detmers; Michael P Graziano; Meredith Hughes; D Euan Macintyre; Anthony Ogawa; Kim A O'neill; Sai Prasad N Iyer; Diane E Shevell; Marsha M Smith; Yui S Tang; Amanda M Makarewicz; Feroze Ujjainwalla; Scott W Altmann; Kevin T Chapman; Nancy A Thornberry
Journal:  Proc Natl Acad Sci U S A       Date:  2005-05-31       Impact factor: 11.205

4.  Ezetimibe, a potent cholesterol absorption inhibitor, normalizes combined dyslipidemia in obese hyperinsulinemic hamsters.

Authors:  M van Heek; T M Austin; C Farley; J A Cook; G G Tetzloff; H R Davis
Journal:  Diabetes       Date:  2001-06       Impact factor: 9.461

5.  Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.

Authors:  Joanna P Davies; Catherine Scott; Kimihiko Oishi; Anastasia Liapis; Yiannis A Ioannou
Journal:  J Biol Chem       Date:  2005-01-25       Impact factor: 5.157

6.  The identification of intestinal scavenger receptor class B, type I (SR-BI) by expression cloning and its role in cholesterol absorption.

Authors:  Scott W Altmann; Harry R Davis; Xiaorui Yao; Maureen Laverty; Douglas S Compton; Li-ji Zhu; James H Crona; Mary Ann Caplen; Lizbeth M Hoos; Glen Tetzloff; Tony Priestley; Duane A Burnett; Catherine D Strader; Michael P Graziano
Journal:  Biochim Biophys Acta       Date:  2002-01-30

7.  Effects of ezetimibe, a new cholesterol absorption inhibitor, on plasma lipids in patients with primary hypercholesterolemia.

Authors:  R H Knopp; H Gitter; T Truitt; H Bays; C V Manion; L J Lipka; A P LeBeaut; R Suresh; B Yang; E P Veltri
Journal:  Eur Heart J       Date:  2003-04       Impact factor: 29.983

8.  Enlargement of high density lipoprotein in mice via liver X receptor activation requires apolipoprotein E and is abolished by cholesteryl ester transfer protein expression.

Authors:  Xian-Cheng Jiang; Thomas P Beyer; Zhiqiang Li; Jin Liu; Wei Quan; Robert J Schmidt; Youyan Zhang; William R Bensch; Patrick I Eacho; Guoqing Cao
Journal:  J Biol Chem       Date:  2003-08-28       Impact factor: 5.157

9.  The effects of ezetimibe on surrogate markers of cholesterol absorption and synthesis in Japanese patients with dyslipidemia.

Authors:  Shinya Hiramitsu; Yoshiaki Ishiguro; Hiroyuki Matsuyama; Kenji Yamada; Kazuo Kato; Manji Noba; Akihisa Uemura; Satoshi Yoshida; Yoshiro Matsubara; Atsushi Kani; Kazuo Hasegawa; Hitoshi Hishida; Yukio Ozaki
Journal:  J Atheroscler Thromb       Date:  2010-01-14       Impact factor: 4.928

10.  Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice.

Authors:  Eric D Labonté; Lisa M Camarota; Juan C Rojas; Ronald J Jandacek; Dean E Gilham; Joanna P Davies; Yiannis A Ioannou; Patrick Tso; David Y Hui; Philip N Howles
Journal:  Am J Physiol Gastrointest Liver Physiol       Date:  2008-08-21       Impact factor: 4.052
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  2 in total

1.  Effects of lipid-lowering drugs on irisin in human subjects in vivo and in human skeletal muscle cells ex vivo.

Authors:  Ioanna Gouni-Berthold; Heiner K Berthold; Joo Young Huh; Reena Berman; Nadine Spenrath; Wilhelm Krone; Christos S Mantzoros
Journal:  PLoS One       Date:  2013-09-02       Impact factor: 3.240

2.  Evolution from adherent to suspension: systems biology of HEK293 cell line development.

Authors:  Magdalena Malm; Rasool Saghaleyni; Magnus Lundqvist; Marco Giudici; Veronique Chotteau; Ray Field; Paul G Varley; Diane Hatton; Luigi Grassi; Thomas Svensson; Jens Nielsen; Johan Rockberg
Journal:  Sci Rep       Date:  2020-11-04       Impact factor: 4.379
  2 in total

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