Literature DB >> 22941614

Quantitative amplification of single-stranded DNA.

Eva-Maria Holstein1, David Lydall.   

Abstract

Single-stranded DNA (ssDNA) intermediates play an important role in processes such as DNA replication and homologous recombination, DNA damage responses, and DNA repair. Using quantitative amplification of ssDNA (QAOS), ssDNA arising during various cellular processes in complex genomes can be quantified at numerous single-copy and repetitive loci. QAOS is a useful tool to gain insights into the cellular processes that involve ssDNA and the roles of proteins in regulating ssDNA production and responses to ssDNA.

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Year:  2012        PMID： 22941614     DOI： 10.1007/978-1-61779-998-3_23

Source DB:  PubMed          Journal:  Methods Mol Biol        ISSN： 1064-3745


  8 in total

1.  BRCA1 promotes unloading of the CMG helicase from a stalled DNA replication fork.

Authors:  David T Long; Vladimir Joukov; Magda Budzowska; Johannes C Walter
Journal:  Mol Cell       Date:  2014-09-11       Impact factor: 17.970

2.  Stalled replication forks generate a distinct mutational signature in yeast.

Authors:  Nicolai B Larsen; Sascha E Liberti; Ivan Vogel; Signe W Jørgensen; Ian D Hickson; Hocine W Mankouri
Journal:  Proc Natl Acad Sci U S A       Date:  2017-08-21       Impact factor: 11.205

3.  The 9-1-1 checkpoint clamp coordinates resection at DNA double strand breaks.

Authors:  Greg H P Ngo; David Lydall
Journal:  Nucleic Acids Res       Date:  2015-04-29       Impact factor: 16.971

4.  In vivo occupancy of mitochondrial single-stranded DNA binding protein supports the strand displacement mode of DNA replication.

Authors:  Javier Miralles Fusté; Yonghong Shi; Sjoerd Wanrooij; Xuefeng Zhu; Elisabeth Jemt; Örjan Persson; Nasim Sabouri; Claes M Gustafsson; Maria Falkenberg
Journal:  PLoS Genet       Date:  2014-12-04       Impact factor: 5.917

5.  Systematic Analysis of the DNA Damage Response Network in Telomere Defective Budding Yeast.

Authors:  Eva-Maria Holstein; Greg Ngo; Conor Lawless; Peter Banks; Matthew Greetham; Darren Wilkinson; David Lydall
Journal:  G3 (Bethesda)       Date:  2017-07-05       Impact factor: 3.154

6.  Interplay between nonsense-mediated mRNA decay and DNA damage response pathways reveals that Stn1 and Ten1 are the key CST telomere-cap components.

Authors:  Eva-Maria Holstein; Kate R M Clark; David Lydall
Journal:  Cell Rep       Date:  2014-05-15       Impact factor: 9.423

7.  The 9-1-1 checkpoint clamp stimulates DNA resection by Dna2-Sgs1 and Exo1.

Authors:  Greg H P Ngo; Lata Balakrishnan; Marion Dubarry; Judith L Campbell; David Lydall
Journal:  Nucleic Acids Res       Date:  2014-08-13       Impact factor: 16.971

8.  The MRX Complex Ensures NHEJ Fidelity through Multiple Pathways Including Xrs2-FHA-Dependent Tel1 Activation.

Authors:  Daichi Iwasaki; Kayoko Hayashihara; Hiroki Shima; Mika Higashide; Masahiro Terasawa; Susan M Gasser; Miki Shinohara
Journal:  PLoS Genet       Date:  2016-03-18       Impact factor: 5.917
  8 in total

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