Literature DB >> 22940885

Targeting the chameleon: a focused look at α-synuclein and its roles in neurodegeneration.

Blanca A Silva1, Leonid Breydo, Vladimir N Uversky.   

Abstract

Entities:  

Mesh：

Substances：

Year:  2012        PMID： 22940885     DOI： 10.1007/s12035-012-8334-1

Source DB:  PubMed          Journal:  Mol Neurobiol        ISSN： 0893-7648            Impact factor:   5.590


× No keyword cloud information.
  181 in total

Review 1.  Filamentous nerve cell inclusions in neurodegenerative diseases: tauopathies and alpha-synucleinopathies.

Authors:  M Goedert
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  1999-06-29       Impact factor: 6.237

2.  Solvent-induced collapse of alpha-synuclein and acid-denatured cytochrome c.

Authors:  A S Morar; A Olteanu; G B Young; G J Pielak
Journal:  Protein Sci       Date:  2001-11       Impact factor: 6.725

3.  Nuclear localization of alpha-synuclein and its interaction with histones.

Authors:  John Goers; Amy B Manning-Bog; Alison L McCormack; Ian S Millett; Sebastian Doniach; Donato A Di Monte; Vladimir N Uversky; Anthony L Fink
Journal:  Biochemistry       Date:  2003-07-22       Impact factor: 3.162

4.  Structure and dynamics of micelle-bound human alpha-synuclein.

Authors:  Tobias S Ulmer; Ad Bax; Nelson B Cole; Robert L Nussbaum
Journal:  J Biol Chem       Date:  2004-12-22       Impact factor: 5.157

Review 5.  Fluorescence as a method to reveal structures and membrane-interactions of amyloidogenic proteins.

Authors:  Larissa A Munishkina; Anthony L Fink
Journal:  Biochim Biophys Acta       Date:  2007-03-28

6.  Environmental risk factors and Parkinson's disease: a case-control study in Taiwan.

Authors:  H H Liou; M C Tsai; C J Chen; J S Jeng; Y C Chang; S Y Chen; R C Chen
Journal:  Neurology       Date:  1997-06       Impact factor: 9.910

7.  Dyrk1A phosphorylates alpha-synuclein and enhances intracellular inclusion formation.

Authors:  Eun Joo Kim; Jee Young Sung; Hyun Jung Lee; Hyewhon Rhim; Masato Hasegawa; Takeshi Iwatsubo; Do Sik Min; Jongsun Kim; Seung R Paik; Kwang Chul Chung
Journal:  J Biol Chem       Date:  2006-09-07       Impact factor: 5.157

Review 8.  Synucleinopathies: clinical and pathological implications.

Authors:  J E Galvin; V M Lee; J Q Trojanowski
Journal:  Arch Neurol       Date:  2001-02

Review 9.  Function and dysfunction of α-synuclein: probing conformational changes and aggregation by single molecule fluorescence.

Authors:  Adam J Trexler; Elizabeth Rhoades
Journal:  Mol Neurobiol       Date:  2012-09-16       Impact factor: 5.590

Review 10.  α-Synuclein posttranslational modification and alternative splicing as a trigger for neurodegeneration.

Authors:  Katrin Beyer; Aurelio Ariza
Journal:  Mol Neurobiol       Date:  2012-08-25       Impact factor: 5.590
View more
  8 in total

1.  Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates.

Authors:  Sean Chia; Patrick Flagmeier; Johnny Habchi; Veronica Lattanzi; Sara Linse; Christopher M Dobson; Tuomas P J Knowles; Michele Vendruscolo
Journal:  Proc Natl Acad Sci U S A       Date:  2017-07-11       Impact factor: 11.205

Review 2.  Amyloid-Forming Properties of Human Apolipoproteins: Sequence Analyses and Structural Insights.

Authors:  Madhurima Das; Olga Gursky
Journal:  Adv Exp Med Biol       Date:  2015       Impact factor: 2.622

3.  Age-dependent aggregation of α-synuclein in the nervous system of gut-brain axis is associated with caspase-1 activation.

Authors:  Qi Hu; Mei Hong; Mengyang Huang; Quan Gong; Xiaofan Zhang; Vladimir N Uversky; Francisco Pan-Montojo; Teng Huang; Honglian Zhou; Suiqiang Zhu
Journal:  Metab Brain Dis       Date:  2022-01-28       Impact factor: 3.655

Review 4.  Alpha-Synuclein Targeting Therapeutics for Parkinson's Disease and Related Synucleinopathies.

Authors:  Sindhu Menon; Sabrina Armstrong; Amir Hamzeh; Naomi P Visanji; Sergio Pablo Sardi; Anurag Tandon
Journal:  Front Neurol       Date:  2022-05-09       Impact factor: 4.086

5.  Tipping the Scale from Disorder to Alpha-helix: Folding of Amphiphilic Peptides in the Presence of Macroscopic and Molecular Interfaces.

Authors:  Cahit Dalgicdir; Christoph Globisch; Christine Peter; Mehmet Sayar
Journal:  PLoS Comput Biol       Date:  2015-08-21       Impact factor: 4.475

Review 6.  Biophysical characterization of α-synuclein and its controversial structure.

Authors:  T Reid Alderson; John L Markley
Journal:  Intrinsically Disord Proteins       Date:  2013-04-01

7.  α-Synuclein phosphorylation at serine 129 occurs after initial protein deposition and inhibits seeded fibril formation and toxicity.

Authors:  Simona S Ghanem; Nour K Majbour; Nishant N Vaikath; Mustafa T Ardah; Daniel Erskine; Nanna Møller Jensen; Muneera Fayyad; Indulekha P Sudhakaran; Eftychia Vasili; Katerina Melachroinou; Ilham Y Abdi; Ilaria Poggiolini; Patricia Santos; Anton Dorn; Paolo Carloni; Kostas Vekrellis; Johannes Attems; Ian McKeith; Tiago F Outeiro; Poul Henning Jensen; Omar M A El-Agnaf
Journal:  Proc Natl Acad Sci U S A       Date:  2022-03-30       Impact factor: 12.779

8.  Elevated α-synuclein caused by SNCA gene triplication impairs neuronal differentiation and maturation in Parkinson's patient-derived induced pluripotent stem cells.

Authors:  L M A Oliveira; L J Falomir-Lockhart; M G Botelho; K-H Lin; P Wales; J C Koch; E Gerhardt; H Taschenberger; T F Outeiro; P Lingor; B Schüle; D J Arndt-Jovin; T M Jovin
Journal:  Cell Death Dis       Date:  2015-11-26       Impact factor: 8.469
  8 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.