Literature DB >> 22940699

Squamous cell carcinoma in an esophageal diverticulum below the aortic arch.

Akiyuki Wakita1, Satoru Motoyama, Yusuke Sato, Kei Yoshino, Tomohiko Sasaki, Hajime Saito, Yoshihiro Minamiya, Jun-Ichi Ogawa.   

Abstract

INTRODUCTION: Esophageal diverticula frequently arise from pharyngoesophageal transition area, tracheal bifurcation and epiphrenic region. Carcinoma arising from esophageal diverticulum is rarely seen. We report a patient with a squamous cell carcinoma arising within an esophageal diverticulum below the aortic arch. PRESENTATION OF CASE: A 70-year-old man was diagnosed to have a squamous cell carcinoma of the vocal cord with enlarged lymph nodes in the neck, as well as a squamous cell carcinoma arising within an esophageal diverticulum below the aortic arch. There have been no reported cases of esophageal cancer arising from a diverticulum below the aortic arch. Preoperative radiotherapy for the esophageal cancer and pharyngeal cancer was given, followed by surgery. The excised specimen of the esophageal diverticulum and its external appearance revealed that it lacked muscle fibers, with a type 0-IIa lesion arising from the diverticulum. Microscopic examination showed three lymph nodes at the superior mediastinum were positive for malignancy. Bilateral pleural dissemination was detected 7 months after esophagectomy. DISCUSSION: Cancer arising from an esophageal diverticulum is mainly found at an advanced stage because of delayed diagnosis. The absence of muscularis propia may lead to early invasion. Thus, cancers within an esophageal diverticulum are considered to be at a more advanced stage than similar cancers arising elsewhere.
CONCLUSION: For detecting of cancer arising from an esophageal diverticulum, a high index of awareness is important. Delay in diagnosis makes surgical management difficult.
Copyright © 2012 Surgical Associates Ltd. Published by Elsevier Ltd. All rights reserved.

Entities:  

Year:  2012        PMID: 22940699      PMCID: PMC3437403          DOI: 10.1016/j.ijscr.2012.07.010

Source DB:  PubMed          Journal:  Int J Surg Case Rep        ISSN: 2210-2612


  6 in total

Review 1.  Pharyngeal pouch (Zenker's diverticulum).

Authors:  M A Siddiq; S Sood; D Strachan
Journal:  Postgrad Med J       Date:  2001-08       Impact factor: 2.401

2.  Squamous cell carcinoma and Zenker diverticulum.

Authors:  B L D M Brücher; M Sarbia; E Oestreicher; M Molls; M Burian; E Biemer; H J Stein
Journal:  Dis Esophagus       Date:  2007       Impact factor: 3.429

3.  Carcinoma arising from an epiphrenic diverticulum: a frequently misdiagnosed disease.

Authors:  Szu-Tsen Lai; Chung-Ping Hsu
Journal:  Ann Thorac Cardiovasc Surg       Date:  2007-04       Impact factor: 1.520

Review 4.  Esophageal diverticula and cancer.

Authors:  F A M Herbella; A Dubecz; M G Patti
Journal:  Dis Esophagus       Date:  2011-07-21       Impact factor: 3.429

5.  Epiphrenic esophageal diverticula: spectrum of symptoms and consequences.

Authors:  Jeremy H Conklin; Deepak Singh; Mark R Katlic
Journal:  J Am Osteopath Assoc       Date:  2009-10

6.  Ten year survival after excision of squamous cell cancer in Zenker's diverticulum: report of a case.

Authors:  Gianlorenzo Dionigi; Fausto Sessa; Francesca Rovera; Luigi Boni; Gianpaolo Carrafiello; Renzo Dionigi
Journal:  World J Surg Oncol       Date:  2006-03-28       Impact factor: 2.754

  6 in total
  1 in total

1.  Squamous cell carcinoma arising in a Zenker diverticulum.

Authors:  Francesca Polit; Hisham F Bahmad; Jessica Wahi; Arunima Deb; Kevin Newsome; Lydia Howard; Robert Poppiti; Kfir Ben-David; Sarah Alghamdi
Journal:  J Surg Case Rep       Date:  2022-09-28
  1 in total

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