| Literature DB >> 2294024 |
N K Cénas1, J A Marcinkeviciene, J J Kulys, S A Usanov.
Abstract
Adrenodoxin stimulated the oxidation of NADPH by 1,4-benzoquinone, catalyzed by NADPH:adrenodoxin reductase. It prevented the enzyme inhibition by NADPH and formed an additional pathway of benzoquinone reduction presumably via reduced adrenodoxin. In the presence of 100-400 microM NADP+, which increased the Km of NADPH, adrenodoxin acted as a partial competitive inhibitor for NADPH decreasing its TN/Km by a limiting factor of 3. Ki of adrenodoxin decreased on the NADP+ concentration decrease and was estimated to be about 10(-8) M in the absence of NADP+.Entities:
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Year: 1990 PMID： 2294024 DOI： 10.1016/0014-5793(90)80042-h
Source DB: PubMed Journal: FEBS Lett ISSN： 0014-5793 Impact factor: 4.124