| Literature DB >> 22940020 |
Anupama Grandhi1, Audrey L Boros, Nicholas Berardo, Renee F Reich, Paul D Freedman.
Abstract
Anaplastic large cell lymphoma (ALCL), a subgroup of T-cell non-Hodgkin's lymphoma, is an uncommon tumor exhibiting CD30 positivity and a characteristic immunophenotypic profile. Histologically, ALCL is characterized by the proliferation of large, anaplastic lymphoid cells with eccentric horseshoe- or kidney-shaped nuclei and one or more prominent nucleoli. Rare cases have been cited in the literature of ALCL presenting primarily in the oral cavity. The purpose of this article was to present 2 instructive cases of CD30+, anaplastic lymphoma kinase-negative ALCL with oral and systemic involvement.Entities:
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Year: 2012 PMID： 22940020 DOI： 10.1016/j.oooo.2012.04.010
Source DB: PubMed Journal: Oral Surg Oral Med Oral Pathol Oral Radiol