Literature DB >> 22936212

Accurately administering oral medication to children isn't child's play.

Victoria L Beckett1, Luke D Tyson, Daniel Carroll, Nigel M Gooding, A W Kelsall.   

Abstract

OBJECTIVE: Parents administer oral medications with various measuring devices including metal teaspoons, calibrated spoons and oral syringes. We aimed to determine which was the most accurate.
DESIGN: Self-controlled, non-randomised, experimental study.
SETTING: Caregivers attending paediatric outpatient clinics.
METHODOLOGY: Caregivers measured 5 ml of 120 mg/5 ml paracetamol suspension using a 5.0 ml metal teaspoon, 5.0 ml calibrated spoon and 5.0 ml oral syringe. Samples were weighed and converted to mls. MAIN OUTCOME MEASURES: The mean volume and variance of volumes were measured for each device.
RESULTS: We recruited 277 caregivers (98% parents). Volumes measured ranged from 0.83-6.52 ml. Accuracy did not vary with caregivers' age, gender, instrument preference, number and age of children. The mean volumes measured with the oral syringe (95% CI 5.09 to 5.17 ml) and metal spoon (95% CI 3.90 to 4.08 ml) were significantly different to the desired 5 ml volume (p<0.0001), dissimilar to the mean volume measured using the calibrated spoon (95% CI 4.91 to 5.09 ml, p=0.99). The variance of volumes measured with the oral syringe (SD 0.348 ml) was significantly smaller (p<0.0001) than that measured using a calibrated spoon (SD 0.762 ml) or metal spoon (SD 0.749 ml).
CONCLUSIONS: The calibrated spoon was the most accurate producing a mean volume of 5 ml, while the oral syringe had the smallest variance. The increased variability of calibrated or metal spoons may result in under or overdosing especially when administering drugs with a narrow therapeutic window. Health care professionals must make a case-by-case decision regarding which device is preferable depending on the medication in question. Parental education could improve measuring accuracy.

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Year:  2012        PMID: 22936212     DOI: 10.1136/archdischild-2012-301850

Source DB:  PubMed          Journal:  Arch Dis Child        ISSN: 0003-9888            Impact factor:   3.791


  5 in total

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2.  Liquid Drug Dosage Measurement Errors with Different Dosing Devices.

Authors:  Pradnya Joshi; Sandeep B Bavdekar
Journal:  Indian J Pediatr       Date:  2019-02-28       Impact factor: 1.967

3.  Molecular diagnosis of long QT syndrome at 10 days of life by rapid whole genome sequencing.

Authors:  James R Priest; Scott R Ceresnak; Frederick E Dewey; Lindsey E Malloy-Walton; Kyla Dunn; Megan E Grove; Marco V Perez; Katsuhide Maeda; Anne M Dubin; Euan A Ashley
Journal:  Heart Rhythm       Date:  2014-06-25       Impact factor: 6.343

4.  Dosing Accuracy of Oral Extemporaneous Suspensions of Antibiotics: Measuring Procedures and Administration Devices.

Authors:  Inês Neves; Maria D Auxtero
Journal:  Pharmaceutics       Date:  2021-04-10       Impact factor: 6.321

5.  A Survey to Understand Parent/Caregiver and Children's Views on Devices Used for the Administration of Oral Pediatric Medicines in Japan.

Authors:  Jumpei Saito; Hidefumi Nakamura; Jennifer Walsh; Akimasa Yamatani; Smita Salunke
Journal:  Children (Basel)       Date:  2022-02-03
  5 in total

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