Literature DB >> 22935459

A rare case of Hodkin's lymphoma of the mediastinum imitating retrosternal goiter--retrospective analysis of the diagnostic process.

Marek Dedecjus1, Anna Kędzierska, Józef Kozak, Radzisław Kordek, Jan Brzeziński.   

Abstract

Primary extranodal sites of development of lymphoid neoplasms are rare and concern about 5% of patients with Hodgkin's lymphoma. Extranodal development is more common in non Hodgkin's lymphoma and may reach 33%. A 27-year-old woman was diagnosed by a cardiologist for a short breath. On the physical examination no other abnormalities were observed. Echocardiography, performed by cardiologist, revealed a large tumor, overlaying the right ventricle and compressing the pulmonary trunk. Chest X-ray, ultrasound and CT-scan confirmed diagnosis. In fine needle aspiration clear, lucid fluid was obtained. Scintygraphy of the neck and thorax showed accumulation of the marker in the properly placed but enlarged thyroid gland. Patient was qualified for surgical treatment - cervicotomy and sternothomy were performed. The histopatological exam of the tumor revealed Hodgkin's lymphoma of the mediastinum (classical subtype NS-1). Following the surgery, adjuvant therapy was instituted. After the treatment PET-CT-scan did not show any kind of non-physiological radiomarker's accumulation in the monitored regions of the body and in in three-years follow-up the patient shows no signs of recurrence.

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Year:  2012        PMID: 22935459     DOI: 10.2478/v10035-012-0061-9

Source DB:  PubMed          Journal:  Pol Przegl Chir        ISSN: 0032-373X


  2 in total

Review 1.  Thyroid nodule as a first manifestation of Hodgkin lymphoma-report of two cases and literature review.

Authors:  Ewelina Szczepanek-Parulska; Malgorzata Szkudlarek; Przemyslaw Majewski; Jan Breborowicz; Marek Ruchala
Journal:  Diagn Pathol       Date:  2013-07-15       Impact factor: 2.644

2.  Myasthenic Crisis Manifesting as Postoperative Respiratory Failure following Resection of Unsuspected Intrathoracic Thymic T-Cell Lymphoma during Thyroidectomy for an Adjacent Large Retrosternal Goiter.

Authors:  Mohamed E Ahmed; Mohamed A Mahgoub; Mohamed G Alnedar; Seif I Mahadi; Maha Alzubeir; Lamyaa A M El Hassan; ElWaleed M Elamin; Ahmed Mohammed El Hassan
Journal:  Eur Thyroid J       Date:  2014-08-09
  2 in total

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