Literature DB >> 22933504

Biological reconstruction after excision, irradiation and reimplantation of diaphyseal tibial tumours using an ipsilateral vascularised fibular graft.

S Mottard1, R J Grimer, A Abudu, S R Carter, R M Tillman, L Jeys, D Spooner.   

Abstract

The purpose of this study was to assess the outcome of 15 patients (mean age 13.6 years (7 to 25)) with a primary sarcoma of the tibial diaphysis who had undergone excision of the affected segment that was then irradiated (90 Gy) and reimplanted with an ipsilateral vascularised fibular graft within it. The mean follow-up was 57 months (22 to 99). The mean time to full weight-bearing was 23 weeks (9 to 57) and to complete radiological union 42.1 weeks (33 to 55). Of the 15 patients, seven required a further operation, four to obtain skin cover. The mean Musculoskeletal Society Tumor Society functional score at final follow-up was 27 out of 30 once union was complete. The functional results were comparable with those of allograft reconstruction and had a similar rate of complication. We believe this to be a satisfactory method of biological reconstruction of the tibial diaphysis in selected patients.

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Mesh:

Year:  2012        PMID: 22933504     DOI: 10.1302/0301-620X.94B9.29164

Source DB:  PubMed          Journal:  J Bone Joint Surg Br        ISSN: 0301-620X


  11 in total

Review 1.  [Extracorporeal irradiation : Reimplantation of bone segments in the treatment of malignant bone tumours].

Authors:  A H Krieg
Journal:  Orthopade       Date:  2017-08       Impact factor: 1.087

2.  The clinical outcomes of extracorporeal irradiated and re-implanted cemented autologous bone graft of femoral diaphysis after tumour resection.

Authors:  Tomoki Nakamura; Adesegun Abudu; Roger J Grimer; Simon R Carter; Lee Jeys; Roger M Tillman
Journal:  Int Orthop       Date:  2012-12-28       Impact factor: 3.075

3.  Outcomes of Intercalary Prosthetic Reconstruction for Pathological Diaphyseal Femoral Fractures Secondary to Metastatic Tumors.

Authors:  Hong-Chao Huang; Yong-Cheng Hu; Deng-Xing Lun; Jun Miao; Feng Wang; Xiong-Gang Yang; Xin-Long Ma
Journal:  Orthop Surg       Date:  2017-06-09       Impact factor: 2.071

4.  Intraoperative Extracorporeal Irradiation and Frozen Treatment on Tumor-bearing Autografts Show Equivalent Outcomes for Biologic Reconstruction.

Authors:  Po-Kuei Wu; Cheng-Fong Chen; Chao-Ming Chen; Yu-Chi Cheng; Shang-Wen Tsai; Tain-Hsiung Chen; Wei-Ming Chen
Journal:  Clin Orthop Relat Res       Date:  2018-04       Impact factor: 4.176

5.  Ferulic acid promotes bone defect repair after radiation by maintaining the stemness of skeletal stem cells.

Authors:  Jia-Wu Liang; Pei-Lin Li; Qian Wang; Song Liao; Wei Hu; Zhi-Dong Zhao; Zhi-Ling Li; Bo-Feng Yin; Ning Mao; Li Ding; Heng Zhu
Journal:  Stem Cells Transl Med       Date:  2021-03-22       Impact factor: 6.940

6.  Autoclaved tumor bone for skeletal reconstruction in paediatric patients: a low cost alternative in developing countries.

Authors:  Masood Umer; Hafiz Muhammad Umer; Irfan Qadir; Haroon Rashid; Rabia Awan; Raza Askari; Shamvil Ashraf
Journal:  Biomed Res Int       Date:  2013-12-18       Impact factor: 3.411

7.  Understanding the potentiality of accelerator based-boron neutron capture therapy for osteosarcoma: dosimetry assessment based on the reported clinical experience.

Authors:  Silva Bortolussi; Ian Postuma; Nicoletta Protti; Lucas Provenzano; Cinzia Ferrari; Laura Cansolino; Paolo Dionigi; Olimpio Galasso; Giorgio Gasparini; Saverio Altieri; Shin-Ichi Miyatake; Sara J González
Journal:  Radiat Oncol       Date:  2017-08-15       Impact factor: 3.481

8.  Bilateral fibular graft: biological reconstruction after resection of primary malignant bone tumors of the lower limb.

Authors:  Maya Niethard; Carmen Tiedke; Dimosthenis Andreou; Frank Traub; Mario Kuhnert; Mathias Werner; Per-Ulf Tunn
Journal:  Sarcoma       Date:  2013-04-16

9.  Successful correction of tibial bone deformity through multiple surgical procedures, liquid nitrogen-pretreated bone tumor autograft, three-dimensional external fixation, and internal fixation in a patient with primary osteosarcoma: a case report.

Authors:  Akihiko Takeuchi; Norio Yamamoto; Toshiharu Shirai; Hideji Nishida; Katsuhiro Hayashi; Koji Watanabe; Shinji Miwa; Hiroyuki Tsuchiya
Journal:  BMC Surg       Date:  2015-12-07       Impact factor: 2.102

10.  Short-term outcomes of reconstruction subsequent to intercalary resection of femoral diaphyseal metastatic tumor with pathological fracture: Comparison between segmental allograft and intercalary prosthesis.

Authors:  Deng-Xing Lun; Yong-Cheng Hu; Xiong-Gang Yang; Feng Wang; Zhao-Wan Xu
Journal:  Oncol Lett       Date:  2018-01-16       Impact factor: 2.967

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