Literature DB >> 22931532

Anthracyclines still prove effective in anticancer therapy.

Mikolaj Piekarski1, Anna Jelińska.   

Abstract

Present-day is developing in many fields. Many pathological processes are better understood, including carcinogenesis. Consequently, the failure of pharmacotherapy aimed at cancerous diseases is becoming explainable. At the same time, new anticancer drugs continue to be introduced. Anthracycline antibiotics are a well-known and widely used group of anticancer drugs. However, in addition to their efficiency they demonstrate severe side effects compounded by the appearance of resistant cells. Therefore, the search for new anthracycline derivatives with improved pharmacodynamic properties and fewer adverse effects is in progress, delivering promising results.

Entities:  

Mesh:

Substances:

Year:  2013        PMID: 22931532     DOI: 10.2174/1389557511313050001

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN: 1389-5575            Impact factor:   3.862


  4 in total

1.  Nitrososynthase-triggered oxidative carbon-carbon bond cleavage in baumycin biosynthesis.

Authors:  Ahmad Al-Mestarihi; Anthony Romo; Hung-wen Liu; Brian O Bachmann
Journal:  J Am Chem Soc       Date:  2013-07-25       Impact factor: 15.419

2.  THE ROLE OF PROTEIN CHAPERONES IN THE SURVIVAL FROM ANTHRACYCLINE-INDUCED OXIDATIVE STRESS IN SACCHAROMYCES CEREVISIAE.

Authors:  Jana S Miles; Samantha J Sojourner; Lahcen Jaafar; Aurellia Whitmore; Selina Darling-Reed; Hernan Flores-Rozas
Journal:  Int J Adv Res (Indore)       Date:  2018-03

3.  Structure of DnmZ, a nitrososynthase in the Streptomyces peucetius anthracycline biosynthetic pathway.

Authors:  Lauren Sartor; Charmaine Ibarra; Ahmad Al-Mestarihi; Brian O Bachmann; Jessica L Vey
Journal:  Acta Crystallogr F Struct Biol Commun       Date:  2015-09-23       Impact factor: 1.056

4.  The influence of pH and temperature on the stability of N-[(piperidine)methylene]daunorubicin Hydrochloride and a comparison of the stability of daunorubicin and its four new amidine derivatives in aqueous solutions.

Authors:  Mikołaj Piekarski; Agnieszka Dołhań; Judyta Cielecka-Piontek; Przemysław Zalewski; Witold Kycler; Aleksandra Kaczmarek; Artur Firlej; Irena Oszczapowicz; Anna Jelińska
Journal:  ScientificWorldJournal       Date:  2014-02-06
  4 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.