Literature DB >> 22931321

Lifelong management of amyloid-beta metabolism to prevent Alzheimer's disease.

Sam Gandy.   

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Year:  2012        PMID： 22931321      PMCID： PMC6464107          DOI： 10.1056/NEJMe1207995

Source DB:  PubMed          Journal:  N Engl J Med        ISSN： 0028-4793            Impact factor:   91.245


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  18 in total

1.  High levels of homocysteine results in cerebral amyloid angiopathy in mice.

Authors:  Jian-Guo Li; Domenico Praticò
Journal:  J Alzheimers Dis       Date:  2015       Impact factor: 4.472

2.  Caspase-3-dependent cleavage of Akt modulates tau phosphorylation via GSK3β kinase: implications for Alzheimer's disease.

Authors:  J Chu; E Lauretti; D Praticò
Journal:  Mol Psychiatry       Date:  2017-01-31       Impact factor: 15.992

3.  Degradation of gamma secretase activating protein by the ubiquitin-proteasome pathway.

Authors:  Jin Chu; Jian-Guo Li; Nicholas E Hoffman; Muniswamy Madesh; Domenico Praticò
Journal:  J Neurochem       Date:  2015-02-13       Impact factor: 5.372

4.  Modulation of Autophagy as a Therapeutic Target for Alzheimer's Disease.

Authors:  John W Steele; Emily Fan; Yildiz Kelahmetoglu; Yuan Tian; Victor Bustos
Journal:  Postdoc J       Date:  2013-02

5.  Gamma secretase-activating protein is a substrate for caspase-3: implications for Alzheimer's disease.

Authors:  Jin Chu; Jian-Guo Li; Yash B Joshi; Phillip F Giannopoulos; Nicholas E Hoffman; Muniswamy Madesh; Domenico Praticò
Journal:  Biol Psychiatry       Date:  2014-06-16       Impact factor: 13.382

6.  GATA1-mediated transcriptional regulation of the γ-secretase activating protein increases Aβ formation in Down syndrome.

Authors:  Jin Chu; Thomas Wisniewski; Domenico Praticò
Journal:  Ann Neurol       Date:  2015-10-29       Impact factor: 10.422

7.  Homocysteine exacerbates β-amyloid pathology, tau pathology, and cognitive deficit in a mouse model of Alzheimer disease with plaques and tangles.

Authors:  Jian-Guo Li; Jin Chu; Carlos Barrero; Salim Merali; Domenico Praticò
Journal:  Ann Neurol       Date:  2014-05-28       Impact factor: 10.422

Review 8.  Mammalian prions and their wider relevance in neurodegenerative diseases.

Authors:  John Collinge
Journal:  Nature       Date:  2016-11-10       Impact factor: 49.962

9.  Early fear memory defects are associated with altered synaptic plasticity and molecular architecture in the TgCRND8 Alzheimer's disease mouse model.

Authors:  John W Steele; Hannah Brautigam; Jennifer A Short; Allison Sowa; Mengxi Shi; Aniruddha Yadav; Christina M Weaver; David Westaway; Paul E Fraser; Peter H St George-Hyslop; Sam Gandy; Patrick R Hof; Dara L Dickstein
Journal:  J Comp Neurol       Date:  2014-07-01       Impact factor: 3.215

10.  Hypothesis-driven genomics pays off.

Authors:  Gregory A Petsko
Journal:  Genome Biol       Date:  2012-10-30       Impact factor: 13.583
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