Literature DB >> 22931313

Diversity oriented synthesis of pyran based polyfunctional stereogenic macrocyles and their conformational studies.

Arya Ajay1, Shrikant Sharma, Munna Prasad Gupt, Vikas Bajpai, Brijesh Kumar, Mahabir Prasad Kaushik, Rituraj Konwar, Ravi Sankar Ampapathi, Rama Pati Tripathi.   

Abstract

A new approach to synthesize a homologous series of 14-, 15-, and 16-membered drug-like, macrocyclic glycoconjugates involving TBAHS promoted azide-propenone intramolecular cycloaddition in designed C-glycopyranosyl butenones from a simple sugar d-glucose and d-mannose is reported.

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Year:  2012        PMID: 22931313     DOI: 10.1021/ol3022275

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  5 in total

1.  Tetrahydroquinoline-derived macrocyclic toolbox: the discovery of antiangiogenesis agents in zebrafish assay.

Authors:  Shiva Krishna Reddy Guduru; Srinivas Chamakuri; Gayathri Chandrasekar; Satish Srinivas Kitambi; Prabhat Arya
Journal:  ACS Med Chem Lett       Date:  2013-05-24       Impact factor: 4.345

Review 2.  Diversity-oriented synthetic strategies applied to cancer chemical biology and drug discovery.

Authors:  Ian Collins; Alan M Jones
Journal:  Molecules       Date:  2014-10-27       Impact factor: 4.411

3.  Synthesis of d-glyco-alkynone derivatives via carbonylative Sonogashira reaction.

Authors:  Mariana P Darbem; C Henrique A Esteves; Isadora M de Oliveira; Joel S Reis; Daniel C Pimenta; Hélio A Stefani
Journal:  RSC Adv       Date:  2019-03-25       Impact factor: 4.036

Review 4.  Macrocyclic drugs and synthetic methodologies toward macrocycles.

Authors:  Xufen Yu; Dianqing Sun
Journal:  Molecules       Date:  2013-05-24       Impact factor: 4.411

5.  De novo macrolide-glycolipid macrolactone hybrids: Synthesis, structure and antibiotic activity of carbohydrate-fused macrocycles.

Authors:  Richard T Desmond; Anniefer N Magpusao; Chris Lorenc; Jeremy B Alverson; Nigel Priestley; Mark W Peczuh
Journal:  Beilstein J Org Chem       Date:  2014-09-17       Impact factor: 2.883

  5 in total

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