Literature DB >> 22930488

Etomidate in the emergency management of hypercortisolemia.

Lip Min Soh, Kirun Gunganah, Scott A Akker, Philip Jones, Hasanin Khachi, Kumbirai Dodzo, William M Drake.   

Abstract

We describe a protocol for etomidate infusion for the emergency management of hypercortisolemia. Etomidate is commenced at 2.5 mg/h and titrated subsequently according to cortisol levels. It is well tolerated without any sedative effects and can be administered safely via peripheral access for use in the general ward setting.

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Year:  2012        PMID: 22930488     DOI: 10.1530/EJE-12-0698

Source DB:  PubMed          Journal:  Eur J Endocrinol        ISSN: 0804-4643            Impact factor:   6.664


  8 in total

Review 1.  The Treatment of Cushing's Disease.

Authors:  Rosario Pivonello; Monica De Leo; Alessia Cozzolino; Annamaria Colao
Journal:  Endocr Rev       Date:  2015-06-11       Impact factor: 19.871

2.  Analogues of etomidate: modifications around etomidate's chiral carbon and the impact on in vitro and in vivo pharmacology.

Authors:  Ervin Pejo; Peter Santer; Spencer Jeffrey; Hilary Gallin; S Shaukat Husain; Douglas E Raines
Journal:  Anesthesiology       Date:  2014-08       Impact factor: 7.892

Review 3.  Role of "old" pharmacological agents in the treatment of Cushing's syndrome.

Authors:  A G Ambrogio; F Cavagnini
Journal:  J Endocrinol Invest       Date:  2016-04-16       Impact factor: 4.256

Review 4.  Targeted Molecular Imaging in Adrenal Disease-An Emerging Role for Metomidate PET-CT.

Authors:  Iosif A Mendichovszky; Andrew S Powlson; Roido Manavaki; Franklin I Aigbirhio; Heok Cheow; John R Buscombe; Mark Gurnell; Fiona J Gilbert
Journal:  Diagnostics (Basel)       Date:  2016-11-18

Review 5.  Update on medical treatment for Cushing's disease.

Authors:  Daniel Cuevas-Ramos; Dawn Shao Ting Lim; Maria Fleseriu
Journal:  Clin Diabetes Endocrinol       Date:  2016-09-13

Review 6.  Pharmacological management of severe Cushing's syndrome: the role of etomidate.

Authors:  Andrea Pence; Megan McGrath; Stephanie L Lee; Douglas E Raines
Journal:  Ther Adv Endocrinol Metab       Date:  2022-02-14       Impact factor: 3.565

7.  Etomidate in the control of severe Cushing's syndrome by neuroendocrine carcinoma.

Authors:  Alfredo Adolfo Reza-Albarrán; Gerson Geovany Andino Ríos; Laura Gabriela Gómez Herrera
Journal:  Clin Case Rep       Date:  2018-03-12

8.  Low-dose etomidate for the management of severe hypercortisolaemia in different clinical scenarios: a case series and review of the literature.

Authors:  Agnieszka Łebek-Szatańska; Karolina M Nowak; Wojciech Zgliczyński; Elżbieta Baum; Agnieszka Żyłka; Lucyna Papierska
Journal:  Ther Adv Endocrinol Metab       Date:  2019-02-08       Impact factor: 3.565

  8 in total

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