Literature DB >> 22929753

[Necrotic bladder following radiotherapy for cervical carcinoma].

Tom J N Hermans1, Karl P J Delaere, Jan Willem Mens, Mark L Paffen.   

Abstract

BACKGROUND: In contrast to proctitis, vaginitis and acute radiation cystitis are late complications of pelvic radiation therapy, rare, more severe and irreversible. CASE DESCRIPTION: A 66-year-old patient presented with progressive renal failure ten years after radiotherapy for carcinoma of the cervix. Ultrasound investigation revealed a bilateral hydroutereronefrosis (grade 4), with narrowing of the ureterovesical junctions and a diffuse thickening of the urinary bladder wall. Biopsy of the bladder wall showed extended necrosis. The diagnosis was a necrotic bladder with bilateral ureteral stenosis without local symptoms. Lifelong renal urinary drainage was indicated.
CONCLUSION: Late obstructive urological complications, such as bladder necrosis and urethral obstruction, are rare following radiotherapy for cervical carcinoma. Ultrasound follow-up can contribute to the early detection of these complications and intervention can prevent further loss of renal function; however, this would not be cost-effective because of the low incidence rate and because these complications appear in the long term.

Entities:  

Mesh:

Year:  2012        PMID: 22929753

Source DB:  PubMed          Journal:  Ned Tijdschr Geneeskd        ISSN: 0028-2162


  3 in total

Review 1.  [Radiation cystitis : Pathophysiology and treatment].

Authors:  S Mühlstädt; N Mohammed; K Weigand; A Schumann; F Kawan; C Göllert; P Fornara
Journal:  Urologe A       Date:  2017-03       Impact factor: 0.639

Review 2.  Cervical necrosis after chemoradiation for cervical cancer: case series and literature review.

Authors:  Ziad Simon Fawaz; Maroie Barkati; Marie-Claude Beauchemin; Philippe Sauthier; Philippe Gauthier; Thu Van Nguyen
Journal:  Radiat Oncol       Date:  2013-09-23       Impact factor: 3.481

3.  Acute Bladder Necrosis after Pelvic Arterial Embolization for Pelvic Trauma: Lessons Learned from Two Cases of Immediate Postembolization Bladder Necrosis.

Authors:  Samuel Washington; E Charles Osterberg; Sean P Elliott; Adam B Hittelman; Benjamin N Breyer
Journal:  Case Rep Urol       Date:  2016-09-05
  3 in total

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