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Literature DB >> 22929522

Analysis of NUP98/NSD1 translocations in adult AML and MDS patients.

F Thol, B Kölking, I H I Hollink, F Damm, M M van den Heuvel-Eibrink, C Michel Zwaan, G Bug, O Ottmann, K Wagner, M Morgan, W K Hofmann, G Göhring, B Schlegelberger, J Krauter, A Ganser, M Heuser.

Abstract

Entities: Disease Gene Species

Mesh：

Substances：

Year: 2012 PMID： 22929522 DOI： 10.1038/leu.2012.249

Source DB: PubMed Journal: Leukemia ISSN： 0887-6924 Impact factor: 11.528

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15 in total

1. Potent co-operation between the NUP98-NSD1 fusion and the FLT3-ITD mutation in acute myeloid leukemia induction.

Authors: Angeliki Thanasopoulou; Alexandar Tzankov; Juerg Schwaller
Journal: Haematologica Date: 2014-06-20 Impact factor: 9.941

2. Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance.

Authors: Liat Goldberg; Sheryl M Gough; Fan Lee; Christine Dang; Robert L Walker; Yuelin J Zhu; Sven Bilke; Marbin Pineda; Masahiro Onozawa; Yang Jo Chung; Paul S Meltzer; Peter D Aplan
Journal: Genes Chromosomes Cancer Date: 2017-03-31 Impact factor: 5.006

3. Low frequency of calreticulin mutations in MDS patients.

Authors: M Heuser; V Panagiota; C Koenecke; B Fehse; H Alchalby; A Badbaran; R Shahswar; M Stadler; M Eder; G Göhring; A Trummer; T Schroeder; G Kobbe; C Thiede; U Platzbecker; B Schlegelberger; N Kroeger; A Ganser; F Thol
Journal: Leukemia Date: 2014-05-21 Impact factor: 11.528

4. NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report.

Authors: Fabiana Ostronoff; Megan Othus; Robert B Gerbing; Michael R Loken; Susana C Raimondi; Betsy A Hirsch; Beverly J Lange; Stephen Petersdorf; Jerald Radich; Frederick R Appelbaum; Alan S Gamis; Todd A Alonzo; Soheil Meshinchi
Journal: Blood Date: 2014-08-21 Impact factor: 22.113

Review 5. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.

Authors: Hartmut Döhner; Elihu Estey; David Grimwade; Sergio Amadori; Frederick R Appelbaum; Thomas Büchner; Hervé Dombret; Benjamin L Ebert; Pierre Fenaux; Richard A Larson; Ross L Levine; Francesco Lo-Coco; Tomoki Naoe; Dietger Niederwieser; Gert J Ossenkoppele; Miguel Sanz; Jorge Sierra; Martin S Tallman; Hwei-Fang Tien; Andrew H Wei; Bob Löwenberg; Clara D Bloomfield
Journal: Blood Date: 2016-11-28 Impact factor: 22.113

6. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.

Authors: Aniruddha J Deshpande; Anagha Deshpande; Amit U Sinha; Liying Chen; Jenny Chang; Ali Cihan; Maurizio Fazio; Chun-Wei Chen; Nan Zhu; Richard Koche; Liuda Dzhekieva; Gloria Ibáñez; Stuart Dias; Deepti Banka; Andrei Krivtsov; Minkui Luo; Robert G Roeder; James E Bradner; Kathrin M Bernt; Scott A Armstrong
Journal: Cancer Cell Date: 2014-11-20 Impact factor: 31.743

Analysis of NUP98/NSD1 translocations in adult AML and MDS patients.

1. Potent co-operation between the NUP98-NSD1 fusion and the FLT3-ITD mutation in acute myeloid leukemia induction.

2. Somatic mutations in murine models of leukemia and lymphoma: Disease specificity and clinical relevance.

3. Low frequency of calreticulin mutations in MDS patients.

4. NUP98/NSD1 and FLT3/ITD coexpression is more prevalent in younger AML patients and leads to induction failure: a COG and SWOG report.

Review 5. Diagnosis and management of AML in adults: 2017 ELN recommendations from an international expert panel.

6. AF10 regulates progressive H3K79 methylation and HOX gene expression in diverse AML subtypes.

7. Transcriptional dynamics of homeobox C11 gene in water buffalo bubalus bubalis.

Review 8. Histone-modifying enzymes: their role in the pathogenesis of acute leukemia and their therapeutic potential.

Review 9. Mechanistic insights and potential therapeutic approaches for NUP98-rearranged hematologic malignancies.

10. H3K36 methyltransferase NSD1 regulates chondrocyte differentiation for skeletal development and fracture repair.