Literature DB >> 22929220

Very long-term results (up to 17 years) with the double-orifice mitral valve repair combined with ring annuloplasty for degenerative mitral regurgitation.

Michele De Bonis1, Elisabetta Lapenna, Roberto Lorusso, Nicola Buzzatti, Nicola Buzzati, Sandro Gelsomino, Maurizio Taramasso, Enrico Vizzardi, Ottavio Alfieri.   

Abstract

OBJECTIVE: The very long-term results of the double-orifice mitral valve repair are unknown. The aim of this study was to assess the late clinical and echocardiographic outcomes of this technique in patients with degenerative mitral regurgitation.
METHODS: From 1993 to 2000, 174 patients with severe degenerative mitral regurgitation were treated with the double-orifice technique combined with ring annuloplasty. Mean age of patients was 52 ± 12.8 years, New York Heart Association class I or II was present in 71% of the patients, atrial fibrillation in 17.2%, and preoperative left ventricular ejection fraction was 59.5% ± 7.5%. Mitral regurgitation was due to anterior leaflet prolapse in 36 patients (20.6%), bileaflet prolapse in 128 (73.5%), and posterior leaflet prolapse in 10 patients (5.7%).
RESULTS: There were no hospital deaths. At hospital discharge, mitral regurgitation was absent or mild in 169 patients (97.1%) and moderate (2+/4+) in 5 patients (2.8%). Mitral stenosis requiring reoperation was detected in 1 patient (0.6%). Clinical and echocardiographic follow-up was 97.1% complete (mean length, 11.5 ± 2.53 years; median, 11.6 years; longest duration, 17.6 years). At 14 years, actuarial survival was 86.9% ± 3.37%, freedom from cardiac death was 95.8% ± 1.54%, and freedom from reoperation was 89.6 ± 2.51%. At the last echocardiographic examination, recurrence of mitral regurgitation ≥3+ was documented in 23 patients (23/169, 13.6%). Freedom from mitral regurgitation ≥3+ at 14 years was 83.8% ± 3.39%. The only predictor of recurrence of mitral regurgitation ≥3+ was residual mitral regurgitation greater than mild at hospital discharge (hazard ratio, 5.7; 95% confidence interval, 1.6-20.6; P = .007).
CONCLUSIONS: The double-orifice repair combined with ring annuloplasty provides very satisfactory long-term results in patients with degenerative mitral regurgitation in the setting of bileaflet and anterior leaflet prolapse.
Copyright © 2012 The American Association for Thoracic Surgery. Published by Mosby, Inc. All rights reserved.

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Year:  2012        PMID: 22929220     DOI: 10.1016/j.jtcvs.2012.07.034

Source DB:  PubMed          Journal:  J Thorac Cardiovasc Surg        ISSN: 0022-5223            Impact factor:   5.209


  8 in total

Review 1.  Contemporary application of the edge-to-edge repair.

Authors:  Alberto Pozzoli; Luca Vicentini; Michele De Bonis; Giovanna Di Giannuario; Giovanni La Canna; Ottavio Alfieri
Journal:  Ann Cardiothorac Surg       Date:  2015-07

2.  Long-term results of the edge-to-edge repair for failed mitral valve repair as a bailout option.

Authors:  Zhaoji Zhong; Ziqi Yue; Zhenhua Zhao; Wu Song; Shanshan Zheng; Sheng Liu
Journal:  Gen Thorac Cardiovasc Surg       Date:  2020-07-11

3.  Interventional vs. surgical mitral valve therapy. Which technique for which patient?

Authors:  M Taramasso; N Buzzatti; G La Canna; A Colombo; O Alfieri; F Maisano
Journal:  Herz       Date:  2013-08       Impact factor: 1.443

Review 4.  A Technical Review of Minimally Invasive Mitral Valve Replacements.

Authors:  Georgia L Preston-Maher; Ryo Torii; Gaetano Burriesci
Journal:  Cardiovasc Eng Technol       Date:  2014-11-25       Impact factor: 2.495

5.  Learning curve of mitral valve repair: cumulative sum failure analysis from single high-volume center.

Authors:  Jun Li; Yun Zhao; Tianyu Zhou; Kai Zhu; Junyu Zhai; Yongxin Sun; Lai Wei; Wenjun Ding; Tao Hong; Hao Lai; Chunsheng Wang
Journal:  J Thorac Dis       Date:  2020-11       Impact factor: 2.895

6.  Commentary: Biomechanical differences after mitral valve repair: Is it time to use the science?

Authors:  Hani Ali-Ghosh; Clifford William Barlow
Journal:  JTCVS Tech       Date:  2021-10-26

7.  Actual perspective on off-pump transapical artificial chord implantation.

Authors:  Matteo Saccocci; Andrea Colli
Journal:  J Card Surg       Date:  2022-02-19       Impact factor: 1.778

8.  Mitral valve repair in complex anatomy and challenging patients: the versatility of the edge to edge concept.

Authors:  M Taramasso; O Alfieri
Journal:  Heart Lung Vessel       Date:  2013
  8 in total

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