| Literature DB >> 22928812 |
Manuel Jörres1, Ingo Schiffers, Iuliana Atodiresei, Carsten Bolm.
Abstract
A series of new thiourea catalysts prepared from natural amino acids have been applied in organocatalytic asymmetric Michael additions of α-nitrocyclohexanone to nitroalkenes. The resulting addition products are formed with excellent enantioselectivities (up to an er of 98:2) in good yields (up to 90%).Entities:
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Year: 2012 PMID： 22928812 DOI： 10.1021/ol302005f
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005