Literature DB >> 2292769

Drug targeting in cancer chemotherapy: a clinical perspective.

P K Gupta1.   

Abstract

Drug targeting is a phenomenon which maneuvers the distribution of drug in the body in such a manner that the major fraction of the drug interacts exclusively with the target tissue at a cellular or subcellular level. Numerous strategies have been developed to accomplish this goal; some of them have been tried clinically for improving cancer chemotherapy. This review updates the current status of research in the area of targeted drug delivery, with particular emphasis on its application in the clinical management of carcinomas.

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Year:  1990        PMID： 2292769     DOI： 10.1002/jps.2600791102

Source DB:  PubMed          Journal:  J Pharm Sci        ISSN： 0022-3549            Impact factor:   3.534


  8 in total

1.  High technology drugs for cancer: the decision process for adding to a formulary.

Authors:  J L Glennie; D M Woloschuk; K W Hall
Journal:  Pharmacoeconomics       Date:  1993-12       Impact factor: 4.981

Review 2.  Pharmacokinetic rationale for chemotherapeutic drugs combined with intra-arterial degradable starch microspheres (Spherex).

Authors:  C J Johansson
Journal:  Clin Pharmacokinet       Date:  1996-09       Impact factor: 6.447

3.  Nanoparticulate delivery of potent microtubule inhibitor for metastatic melanoma treatment.

Authors:  Jitender Bariwal; Virender Kumar; Hao Chen; Rajan Sharma Bhattarai; Yang Peng; Wei Li; Ram I Mahato
Journal:  J Control Release       Date:  2019-07-19       Impact factor: 9.776

4.  Immunotargeting of liposomes containing lipophilic antitumor prodrugs.

Authors:  A Mori; S J Kennel; L Huang
Journal:  Pharm Res       Date:  1993-04       Impact factor: 4.200

5.  Preparation of adriamycin magnetic albumin microspheres and their experimental antitumor effects in vitro and in vivo.

Authors:  K Tao; D Chen; J Chen; Y Tian; Z Wu; X Wang; X Yang
Journal:  J Tongji Med Univ       Date:  1999

6.  Tissue distribution of methotrexate following administration as a solution and as a magnetic microsphere conjugate in rats bearing brain tumors.

Authors:  D Devineni; A Klein-Szanto; J M Gallo
Journal:  J Neurooncol       Date:  1995       Impact factor: 4.130

7.  Inhalation of an ethanol-based zileuton formulation provides a reduction of pulmonary adenomas in the A/J mouse model.

Authors:  Kelly L Karlage; Erik Mogalian; Annikka Jensen; Paul B Myrdal
Journal:  AAPS PharmSciTech       Date:  2010-01-26       Impact factor: 3.246

Review 8.  An overview and bibliometric analysis on the colorectal cancer therapy by magnetic functionalized nanoparticles for the responsive and targeted drug delivery.

Authors:  Mahdieh Darroudi; Mehrdad Gholami; Majid Rezayi; Majid Khazaei
Journal:  J Nanobiotechnology       Date:  2021-11-29       Impact factor: 10.435
  8 in total

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