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Literature DB >> 2292658

Hypoglycemia, hormones and cytokines in fatal meningococcal septicemia.

J A Romijn¹, M H Godfried, C Wortel, H P Sauerwein.

Abstract

A unique case report with sequential measurements of the plasma concentrations of glucoregulatory hormones, interleukin-6 and tumor necrosis factor during development of hypoglycemia in fatal meningococcemia is presented. Hormonal explanations for hypoglycemia like hyperinsulinemia or defective hypoglycemic counter-regulation were excluded. Plasma concentrations of interleukin-6 and tumor necrosis factor were skyhigh. The putative relation between cytokines and hypoglycemia in sepsis is discussed.

Entities: Disease Gene

Mesh：

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Year: 1990 PMID： 2292658 DOI： 10.1007/BF03349613

Source DB: PubMed Journal: J Endocrinol Invest ISSN： 0391-4097 Impact factor: 4.256

32 in total

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1. Hyperpyrexia due to meningococcal septicaemia treated with cold peritoneal lavage.

Authors: I H Khan; I S Henderson; R A Mactier
Journal: Postgrad Med J Date: 1992-02 Impact factor: 2.401

Review 2. Update on meningococcal disease with emphasis on pathogenesis and clinical management.

Authors: M van Deuren; P Brandtzaeg; J W van der Meer
Journal: Clin Microbiol Rev Date: 2000-01 Impact factor: 26.132

3. Tolerance to endotoxin-induced expression of the interleukin-1 beta gene in blood neutrophils of humans with the sepsis syndrome.

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4. Suppression of hepatic glucose production by human neutrophil alpha-defensins through a signaling pathway distinct from insulin.

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5. Hypoglycemia and Risk Factors for Death in 13 Years of Pediatric Admissions in Mozambique.

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Review 6. Reprogramming of basic metabolic pathways in microbial sepsis: therapeutic targets at last?

Authors: Lise Van Wyngene; Jolien Vandewalle; Claude Libert
Journal: EMBO Mol Med Date: 2018-08 Impact factor: 12.137

Review 7. Metabolic Alterations in Sepsis.

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Journal: J Clin Med Date: 2021-05-29 Impact factor: 4.241

7 in total