Literature DB >> 22926422

Sex for fun: a synthesis of human and animal neurobiology.

Janniko R Georgiadis1, Morten L Kringelbach, James G Pfaus.   

Abstract

Sex is a fundamental pleasure, and crucial to the survival of our species. Though not many people would disagree with the proposition that sexual behaviour depends on the brain, the neuroscientific study of human sex is still relatively taboo and much remains to be discovered. On the contrary, excellent experimental animal models (mostly rat) are available that have uncovered major behavioural, neurochemical, and neuroanatomical characteristics of sexual behaviour. Restructuring sexual behaviour into broader terms reflecting behavioural states (wanting, liking, and inhibition) facilitates species comparison, revealing many similarities between animal and human sexual pleasure cycles, some of which can serve as potential avenues of new human sex research. In particular, behavioural and brain evidence clearly shows that motivational and consummatory phases are fundamentally distinct, and that genitally-induced sexual reward is a major factor in sexual learning mechanisms.

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Year:  2012        PMID: 22926422     DOI: 10.1038/nrurol.2012.151

Source DB:  PubMed          Journal:  Nat Rev Urol        ISSN: 1759-4812            Impact factor:   14.432


  118 in total

Review 1.  The dual control model of male sexual response: a theoretical approach to centrally mediated erectile dysfunction.

Authors:  J Bancroft; E Janssen
Journal:  Neurosci Biobehav Rev       Date:  2000-07       Impact factor: 8.989

2.  Neural correlates of conscious self-regulation of emotion.

Authors:  M Beauregard; J Lévesque; P Bourgouin
Journal:  J Neurosci       Date:  2001-09-15       Impact factor: 6.167

Review 3.  Changing paradigms from a historical DSM-III and DSM-IV view toward an evidence-based definition of premature ejaculation. Part II--proposals for DSM-V and ICD-11.

Authors:  Marcel D Waldinger; Dave H Schweitzer
Journal:  J Sex Med       Date:  2006-07       Impact factor: 3.802

Review 4.  Inhibitory and disinhibitory effects of psychomotor stimulants and depressants on the sexual behavior of male and female rats.

Authors:  James G Pfaus; Mark F Wilkins; Nina Dipietro; Michael Benibgui; Rachel Toledano; Anna Rowe; Melissa Castro Couch
Journal:  Horm Behav       Date:  2009-10-22       Impact factor: 3.587

5.  The male orgasm: pelvic contractions measured by anal probe.

Authors:  J G Bohlen; J P Held; M O Sanderson
Journal:  Arch Sex Behav       Date:  1980-12

6.  Descending projections of infralimbic cortex that mediate stimulation-evoked changes in arterial pressure.

Authors:  G D Fisk; J M Wyss
Journal:  Brain Res       Date:  2000-03-17       Impact factor: 3.252

7.  Sex and context: hormones and primate sexual motivation.

Authors:  K Wallen
Journal:  Horm Behav       Date:  2001-09       Impact factor: 3.587

8.  Context-dependent acquisition of copulatory behavior in the male rat: role of female availability.

Authors:  Nafissa Ismail; Yue Zhao; James G Pfaus
Journal:  Behav Neurosci       Date:  2008-10       Impact factor: 1.912

9.  Gene-gene interaction associated with neural reward sensitivity.

Authors:  Juliana Yacubian; Tobias Sommer; Katrin Schroeder; Jan Gläscher; Raffael Kalisch; Boris Leuenberger; Dieter F Braus; Christian Büchel
Journal:  Proc Natl Acad Sci U S A       Date:  2007-05-02       Impact factor: 11.205

10.  Distress about sex: a national survey of women in heterosexual relationships.

Authors:  John Bancroft; Jeni Loftus; J Scott Long
Journal:  Arch Sex Behav       Date:  2003-06
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  39 in total

1.  Impact of COMT Val158Met-polymorphism on appetitive conditioning and amygdala/prefrontal effective connectivity.

Authors:  Tim Klucken; Onno Kruse; Sina Wehrum-Osinsky; Juergen Hennig; Jan Schweckendiek; Rudolf Stark
Journal:  Hum Brain Mapp       Date:  2014-11-13       Impact factor: 5.038

Review 2.  Dopamine and addiction: what have we learned from 40 years of research.

Authors:  Marcello Solinas; Pauline Belujon; Pierre Olivier Fernagut; Mohamed Jaber; Nathalie Thiriet
Journal:  J Neural Transm (Vienna)       Date:  2018-12-19       Impact factor: 3.575

3.  Subcortical BOLD responses during visual sexual stimulation vary as a function of implicit porn associations in women.

Authors:  Charmaine Borg; Peter J de Jong; Janniko R Georgiadis
Journal:  Soc Cogn Affect Neurosci       Date:  2012-10-09       Impact factor: 3.436

4.  The Affective Core of Emotion: Linking Pleasure, Subjective Well-Being, and Optimal Metastability in the Brain.

Authors:  Morten L Kringelbach; Kent C Berridge
Journal:  Emot Rev       Date:  2017-06-15

Review 5.  Sex differences in the brain: Implications for behavioral and biomedical research.

Authors:  Elena Choleris; Liisa A M Galea; Farida Sohrabji; Karyn M Frick
Journal:  Neurosci Biobehav Rev       Date:  2018-02       Impact factor: 8.989

6.  Differential disruption of conditioned ejaculatory preference in the male rat based on different sensory modalities by micro-infusions of naloxone to the medial preoptic area or ventral tegmental area.

Authors:  Gonzalo R Quintana; Morgan Birrel; Sarah Marceau; Narges Kalantari; James Bowden; Yvonne Bachoura; Eric Borduas; Valerie Lemay; Jason W Payne; Conall Mac Cionnaith; James G Pfaus
Journal:  Psychopharmacology (Berl)       Date:  2019-07-29       Impact factor: 4.530

7.  Anhedonia Following Early-Life Adversity Involves Aberrant Interaction of Reward and Anxiety Circuits and Is Reversed by Partial Silencing of Amygdala Corticotropin-Releasing Hormone Gene.

Authors:  Jessica L Bolton; Jenny Molet; Limor Regev; Yuncai Chen; Neggy Rismanchi; Elizabeth Haddad; Derek Z Yang; Andre Obenaus; Tallie Z Baram
Journal:  Biol Psychiatry       Date:  2017-09-07       Impact factor: 13.382

8.  A neuroscience perspective on sexual risk behavior in adolescence and emerging adulthood.

Authors:  Elizabeth C Victor; Ahmad R Hariri
Journal:  Dev Psychopathol       Date:  2015-11-27

Review 9.  Neuroscience of affect: brain mechanisms of pleasure and displeasure.

Authors:  Kent C Berridge; Morten L Kringelbach
Journal:  Curr Opin Neurobiol       Date:  2013-01-31       Impact factor: 6.627

10.  Brain Activity Unique to Orgasm in Women: An fMRI Analysis.

Authors:  Nan J Wise; Eleni Frangos; Barry R Komisaruk
Journal:  J Sex Med       Date:  2017-10-03       Impact factor: 3.802

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