Literature DB >> 22926362

Is adenomyosis associated with the risk of endometrial cancer?

Ismet Gün1, Oznur Oner, Serkan Bodur, Ozkan Ozdamar, Vedat Atay.   

Abstract

AIM: To evaluate an association of adenomyosis with endometrial cancer and to determine the frequency of adenomyosis at hysterectomy specimens.
METHODS: This study was carried out retrospectively on pathologic specimens of hysterectomies. A total of 472 women in the period 2007-2011 enrolled to the study. All pathologies seen in hysterectomy specimens were noted. The frequency of adenomyosis and the accompanying pathologies were determined. These women were categorized into two groups according to the presence of adenomyosis. The incidence of adenomyosis was analyzed together with the endometrial cancer.
RESULTS: The incidence of adenomyosis was 20.8% at hysterectomy specimens. There was no statistically significant difference between the mean age of the two groups (p = 0.069). There were 98 cases with adenomyosis and the only pathologic finding was adenomyosis, in 28 (28.5%) cases. The most common accompanying pathologies with adenomyosis were uterine myomas in 51 (52%), uterine polyps in 16 (16.3%) and endometrial carcinomas in 11 (11.2%) cases. However, statistically significant association of the presence of adenomyosis with uterine myoma (p = 0.227) and endometrial polyps (p = 0.997) and endometrial carcinoma (p = 0.771) was not found.
CONCLUSION: In hysterectomy specimens, no statistically significant difference was determined between the groups with and without adenomyosis in terms of co-occurrence with endometrial carcinoma.

Entities:  

Mesh:

Year:  2012        PMID: 22926362

Source DB:  PubMed          Journal:  Med Glas (Zenica)        ISSN: 1840-0132


  3 in total

1.  Coexistence of adenomyosis and endometrioid endometrial cancer: Role in surgical guidance and prognosis estimation.

Authors:  Salvatore Gizzo; Tito Silvio Patrelli; Andrea Dall'asta; Stefania DI Gangi; Giovanna Giordano; Costanza Migliavacca; Michela Monica; Carla Merisio; Giovanni Battista Nardelli; Michela Quaranta; Marco Noventa; Roberto Berretta
Journal:  Oncol Lett       Date:  2015-12-15       Impact factor: 2.967

2.  Women with adenomyosis are at higher risks of endometrial and thyroid cancers: A population-based historical cohort study.

Authors:  Chih-Ching Yeh; Fu-Hsiung Su; Chii-Ruey Tzeng; Chih-Hsin Muo; Wen-Chang Wang
Journal:  PLoS One       Date:  2018-03-09       Impact factor: 3.240

Review 3.  Ectopic Endometrium: The Pathologist's Perspective.

Authors:  Alessandra Camboni; Etienne Marbaix
Journal:  Int J Mol Sci       Date:  2021-10-11       Impact factor: 5.923

  3 in total

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