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Literature DB >> 229259

The nonstructural component of the Abelson murine leukemia virus polyprotein P120 is encoded by newly acquired genetic sequences.

W J Van de Ven, F H Reynolds, R P Nalewaik, J R Stephenson.

Abstract

The Abelson leukemia virus (AbLV) polyprotein P120 is compared to translational products representing the entire Moloney murine leukemia virus (MuLV) genome on the basis of [35S]methionine tryptic peptide composition. Three methionine-containing tryptic peptides present in Moloney Pr65gag are each shown to be present in both Pr75gag and in Pr180gag-pol. Of these, one peptide, corresponding to Moloney MuLV p12, but neither of two p30-specific peptides are present in AbLV P120. Among the 12 remaining methionine-containing peptides present in AbLV P120, many, if not all, are unique to AbLV P120 and not shared by either Moloney MuLV Pr180gag-pol or Pr82gag.

Entities: Chemical Disease Species

Mesh：

Substances：
Viral Proteins

Year: 1979 PMID： 229259 PMCID： PMC525955

Source DB: PubMed Journal: J Virol ISSN： 0022-538X Impact factor: 5.103

13 in total

1. Abelson murine leukemia virus-infected cell lines defective in transformation.

Authors: T L Sacks; E J Hershey; J R Stephenson
Journal: Virology Date: 1979-09 Impact factor: 3.616

2. In vitro transformation of lymphoid cells by Abelson murine leukemia virus.

Authors: N Rosenberg; D Baltimore; C D Scher
Journal: Proc Natl Acad Sci U S A Date: 1975-05 Impact factor: 11.205

3. Protein kinase activity associated with the avian sarcoma virus src gene product.

Authors: M S Collett; R L Erikson
Journal: Proc Natl Acad Sci U S A Date: 1978-04 Impact factor: 11.205

4. Identification of an Abelson murine leukemia virus-encoded protein present in transformed fibroblast and lymphoid cells.

Authors: O N Witte; N Rosenberg; M Paskind; A Shields; D Baltimore
Journal: Proc Natl Acad Sci U S A Date: 1978-05 Impact factor: 11.205

5. Translation of type C viral RNAs in Xenopus laevis oocytes: evidence that the 120,000-molecular-weight polyprotein expressed in Abelson leukemia virus-transformed cells is virus coded.

Authors: R K Reynolds; W J van de Ven; J R Stephenson
Journal: J Virol Date: 1978-11 Impact factor: 5.103

6. Evidence that the transforming gene of avian sarcoma virus encodes a protein kinase associated with a phosphoprotein.

Authors: A D Levinson; H Oppermann; L Levintow; H E Varmus; J M Bishop
Journal: Cell Date: 1978-10 Impact factor: 41.582

7. Cells nonproductively transformed by Abelson murine leukemia virus express a high molecular weight polyprotein containing structural and nonstructural components.

Authors: F H Reynolds; T L Sacks; D N Deobagkar; J R Stephenson
Journal: Proc Natl Acad Sci U S A Date: 1978-08 Impact factor: 11.205

8. Murine leukemia virus (T-8)-transformed cells: identification of a precursor polyprotein containing gag gene-coded proteins (p15 and p12) and a nonstructural component.

Authors: T L Sacks; F H Reynolds; D N Deobagkar; J R Stephenson
Journal: J Virol Date: 1978-09 Impact factor: 5.103

2. Evidence that there exist four classes of RNA tumor viruses which encode proteins with associated tyrosine protein kinase activities.

Authors: T Patschinsky; B M Sefton
Journal: J Virol Date: 1981-07 Impact factor: 5.103

3. Identification of tryptic peptides unique to a 110,000-molecular weight polyprotein encoded by the T-8 isolate of murine leukemia virus.

Authors: W J van de Ven; F H Reynolds; J Blomberg; J R Stephenson
Journal: J Exp Med Date: 1980-12-01 Impact factor: 14.307

3 in total