Literature DB >> 22925487

[Intensity modulated radiotherapy for breast cancer].

O Riou1, P Fenoglietto, C Lemanski, D Azria.   

Abstract

Intensity modulated radiotherapy (IMRT) is a technique allowing dose escalation and normal tissue sparing for various cancer types. For breast cancer, the main goals when using IMRT were to improve dose homogeneity within the breast and to enhance coverage of complex target volumes. Nonetheless, better heart and lung protections are achievable with IMRT as compared to standard irradiation for difficult cases. Three prospective randomized controlled trials of IMRT versus standard treatment showed that a better breast homogeneity can translate into better overall cosmetic results. Dosimetric and clinical studies seem to indicate a benefit of IMRT for lymph nodes irradiation, bilateral treatment, left breast and chest wall radiotherapy, or accelerated partial breast irradiation. The multiple technical IMRT solutions available tend to indicate a widespread use for breast irradiation. Nevertheless, indications for breast IMRT should be personalized and selected according to the expected benefit for each individual.
Copyright © 2012 Société française de radiothérapie oncologique (SFRO). Published by Elsevier SAS. All rights reserved.

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Year:  2012        PMID: 22925487     DOI: 10.1016/j.canrad.2012.05.010

Source DB:  PubMed          Journal:  Cancer Radiother        ISSN: 1278-3218            Impact factor:   1.018


  3 in total

1.  Feasibility of accelerated partial breast irradiation with volumetric-modulated arc therapy in elderly and frail patients.

Authors:  Olivier Riou; Pascal Fenoglietto; Céline Bourgier; Olivier Lauche; Fatiha Boulbair; Marie Charissoux; Angélique Ducteil; Norbert Aillères; Claire Lemanski; David Azria
Journal:  Radiat Oncol       Date:  2015-10-14       Impact factor: 3.481

2.  Intensity-modulated radiation therapy with simultaneous integrated boost for locally advanced breast cancer: a prospective study on toxicity and quality of life.

Authors:  David Pasquier; Florence Le Tinier; Raoudha Bennadji; Anais Jouin; Samy Horn; Alexandre Escande; Emmanuelle Tresch; Marie Pierre Chauvet; Audrey Mailliez; Frederik Crop; Xavier Mirabel; Eric Lartigau
Journal:  Sci Rep       Date:  2019-02-26       Impact factor: 4.379

3.  Correlation between toxicity and dosimetric parameters for adjuvant intensity modulated radiation therapy of breast cancer: a prospective study.

Authors:  David Pasquier; Benoit Bataille; Florence Le Tinier; Raoudha Bennadji; Hélène Langin; Alexandre Escande; Emmanuelle Tresch; Franck Darloy; Damien Carlier; Frederik Crop; Eric Lartigau
Journal:  Sci Rep       Date:  2021-02-11       Impact factor: 4.379

  3 in total

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