Literature DB >> 22924707

A multipathway coupled domino strategy: metal-free oxidative cyclization for one-pot synthesis of 2-acylbenzothiazoles from multiform substrates.

Yan-ping Zhu1, Feng-cheng Jia, Mei-cai Liu, An-xin Wu.   

Abstract

A multipathway coupled domino strategy has been developed for the efficient synthesis of 2-acylbenzothiazoles from multiform substrates arylethenes, arylacetylenes, 2-hydroxy-aromatic ketones, and carbinols via four distinct pathways. Through a logical coupled oxidation/heterocyclization domino process, a variety of 2-acylbenzothiazoles were synthesized free of metal in one pot.

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Year:  2012        PMID： 22924707     DOI： 10.1021/ol301921t

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  3 in total

1.  One-Flask Synthesis of Pyrazolo[3,4-d]pyrimidines from 5-Aminopyrazoles and Mechanistic Study.

Authors:  Wan-Ping Yen; Shuo-En Tsai; Naoto Uramaru; Hiroyuki Takayama; Fung Fuh Wong
Journal:  Molecules       Date:  2017-05-16       Impact factor: 4.411

2.  A Novel PIFA/KOH Promoted Approach to Synthesize C2-arylacylated Benzothiazoles as Potential Drug Scaffolds.

Authors:  Xiao-Tong Sun; Zhi-Gang Hu; Zhen Huang; Ling-Li Zhou; Jian-Quan Weng
Journal:  Molecules       Date:  2022-01-22       Impact factor: 4.411

3.  A multi pathway coupled domino strategy: I2/TBHP-promoted synthesis of imidazopyridines and thiazoles via sp3, sp2 and sp C-H functionalization.

Authors:  Yishou Wang; Shichen Li; Xinfeng Wang; Yiming Yao; Lei Feng; Chen Ma
Journal:  RSC Adv       Date:  2022-02-17       Impact factor: 3.361
  3 in total

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