Literature DB >> 22924464

Clinical implementation of systematic medication reconciliation and review as part of the Lund Integrated Medicines Management model--impact on all-cause emergency department revisits.

L M Hellström1, P Höglund, A Bondesson, G Petersson, T Eriksson.   

Abstract

WHAT IS KNOWN AND
OBJECTIVE: Interventions involving medication reconciliation and review by clinical pharmacists can reduce drug-related problems and improve therapeutic outcomes. The objective of this study was to examine the impact of routine admission medication reconciliation and inpatient medication review on emergency department (ED) revisits after discharge. Secondary outcomes included the combined rate of post-discharge hospital revisits or death.
METHODS: This prospective, controlled study included all patients hospitalized in three internal medicine wards in a university hospital, between 1 January 2006 and 31 May 2008. Medication reconciliation on admission and inpatient medication review, conducted by clinical pharmacists in a multiprofessional team, were implemented in these wards at different times during 2007 and 2008 (intervention periods). A discharge medication reconciliation was undertaken in all the study wards, during both control and intervention periods. Patients were included in the intervention group (n = 1216) if they attended a ward with medication reconciliation and review, whether they had received the intervention or not. Control patients (n = 2758) attended the wards before implementation of the intervention. RESULTS AND DISCUSSION: No impact of medication reconciliation and reviews on ED revisits [hazard ratio (HR), 0.95; 95% confidence interval (CI), 0.86-1.04]or event-free survival (HR, 0.96; 95% CI, 0.88-1.04) was demonstrated. In the intervention group, 594 patients (48.8%) visited the ED, compared with 1416 (51.3%) control patients. In total, 716 intervention (58.9%) and 1688 (61.2%) control patients experienced any event (ED visit, hospitalization or death). Because the time to a subsequent ED visit was longer for the control as well as the intervention groups in 2007 than in 2006 (P < 0.05), we re-examined this cohort of patients; the proportion of patients revisiting the ED was similar in both groups in 2007 (P = 0.608). WHAT IS NEW AND
CONCLUSION: Routine implementation of medication reconciliation and reviews on admission and during the hospital stay did not appear to have any impact on ED revisits, re-hospitalizations or mortality over 6-month follow-up.
© 2012 Blackwell Publishing Ltd.

Entities:  

Mesh:

Year:  2012        PMID: 22924464     DOI: 10.1111/jcpt.12001

Source DB:  PubMed          Journal:  J Clin Pharm Ther        ISSN: 0269-4727            Impact factor:   2.512


  12 in total

1.  The utility of a medical admissions pharmacist in a hospital in Australia.

Authors:  Sally B Marotti; Rachael May Theng Cheh; Anne Ponniah; Helen Phuong
Journal:  Int J Clin Pharm       Date:  2017-03-15

2.  Promoting clinical pharmacy services through advanced medication review in the emergency department.

Authors:  Ana de Lorenzo-Pinto; Raquel García-Sánchez; Ana Herranz; Iria Miguens; María Sanjurjo-Sáez
Journal:  Eur J Hosp Pharm       Date:  2018-10-09

3.  Prospective observational study of medication reviews in internal medicine wards: evaluation of drug-related problems.

Authors:  Lina Hellström; Tommy Eriksson; Åsa Bondesson
Journal:  Eur J Hosp Pharm       Date:  2020-11-16

4.  Impact of medication reconciliation and review and counselling, on adverse drug events and healthcare resource use.

Authors:  Amna Al-Hashar; Ibrahim Al-Zakwani; Tommy Eriksson; Alaa Sarakbi; Badriya Al-Zadjali; Saif Al Mubaihsi; Mohammed Al Za'abi
Journal:  Int J Clin Pharm       Date:  2018-05-12

Review 5.  Effectiveness of pharmacist-led medication reconciliation programmes on clinical outcomes at hospital transitions: a systematic review and meta-analysis.

Authors:  Alemayehu B Mekonnen; Andrew J McLachlan; Jo-Anne E Brien
Journal:  BMJ Open       Date:  2016-02-23       Impact factor: 2.692

6.  Motivational Interviewing and Medication Review in Coronary Heart Disease (MIMeRiC): Protocol for a Randomized Controlled Trial Investigating Effects on Clinical Outcomes, Adherence, and Quality of Life.

Authors:  Malin Johansson Östbring; Tommy Eriksson; Göran Petersson; Lina Hellström
Journal:  JMIR Res Protoc       Date:  2018-02-20

Review 7.  The impact of pharmacists-led medicines reconciliation on healthcare outcomes in secondary care: A systematic review and meta-analysis of randomized controlled trials.

Authors:  Ejaz Cheema; Farah Kais Alhomoud; Amnah Shams Al-Deen Kinsara; Jomanah Alsiddik; Marwah Hassan Barnawi; Morooj Abdullah Al-Muwallad; Shatha Abdulbaset Abed; Mahmoud E Elrggal; Mahmoud M A Mohamed
Journal:  PLoS One       Date:  2018-03-28       Impact factor: 3.240

8.  Clinical Outcomes Used in Clinical Pharmacy Intervention Studies in Secondary Care.

Authors:  Lene Juel Kjeldsen; Charlotte Olesen; Merete Kjær Hansen; Trine Rune Høgh Nielsen
Journal:  Pharmacy (Basel)       Date:  2017-05-20

9.  Motivational Interviewing and Medication Review in Coronary Heart Disease (MIMeRiC): Intervention Development and Protocol for the Process Evaluation.

Authors:  Malin Johansson Östbring; Tommy Eriksson; Göran Petersson; Lina Hellström
Journal:  JMIR Res Protoc       Date:  2018-01-30

10.  An inventory of collaborative medication reviews for older adults - evolution of practices.

Authors:  A Kiiski; M Airaksinen; A Mäntylä; S Desselle; A Kumpusalo-Vauhkonen; T Järvensivu; M Pohjanoksa-Mäntylä
Journal:  BMC Geriatr       Date:  2019-11-21       Impact factor: 3.921

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