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Literature DB >> 22923101

Cell migration: regulation of cytoskeleton by Rap1 in Dictyostelium discoideum.

Abstract

Cell movement involves a coordinated regulation of the cytoskeleton, F-actin-mediated protrusions at the front and myosin-mediated contraction of the posterior of a cell. The small GTPase Rap1 functions as a key regulator in the spatial and temporal control of cytoskeleton reorganization for cell migration. This review outlines the establishment of cell polarity by differential localizations of the cytoskeleton and discusses the spatial and temporal regulation of cytoskeleton reorganization via the Rap1 signaling pathway during chemotaxis with a focus on recent advances in the study of chemotaxis using a simple eukaryotic model organism, Dictyostelium discoideum.

Entities: Gene Species

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Year: 2012 PMID： 22923101 DOI： 10.1007/s12275-012-2246-7

Source DB: PubMed Journal: J Microbiol ISSN： 1225-8873 Impact factor: 3.422

44 in total

1. RasGEF-containing proteins GbpC and GbpD have differential effects on cell polarity and chemotaxis in Dictyostelium.

Authors: Leonard Bosgraaf; Arjen Waijer; Ruchira Engel; Antonie J W G Visser; Deborah Wessels; David Soll; Peter J M van Haastert
Journal: J Cell Sci Date: 2005-04-12 Impact factor: 5.285

Review 2. Rap1: a key regulator in cell-cell junction formation.

Authors: Matthijs R H Kooistra; Nadia Dubé; Johannes L Bos
Journal: J Cell Sci Date: 2007-01-01 Impact factor: 5.285

Review 3. New mechanisms and functions of actin nucleation.

Authors: Elif Nur Firat-Karalar; Matthew D Welch
Journal: Curr Opin Cell Biol Date: 2010-11-17 Impact factor: 8.382

4. Regulation of Rap1 activity is required for differential adhesion, cell-type patterning and morphogenesis in Dictyostelium.

Authors: Katie Parkinson; Parvin Bolourani; David Traynor; Nicola L Aldren; Robert R Kay; Gerald Weeks; Christopher R L Thompson
Journal: J Cell Sci Date: 2009-01-06 Impact factor: 5.285

5. Capping of surface receptors and concomitant cortical tension are generated by conventional myosin.

Authors: C Pasternak; J A Spudich; E L Elson
Journal: Nature Date: 1989-10-12 Impact factor: 49.962

6. Multiple myosin II heavy chain kinases: roles in filament assembly control and proper cytokinesis in Dictyostelium.

Authors: Shigehiko Yumura; Masashi Yoshida; Venkaiah Betapudi; Lucila S Licate; Yoshiaki Iwadate; Akira Nagasaki; Taro Q P Uyeda; Thomas T Egelhoff
Journal: Mol Biol Cell Date: 2005-06-29 Impact factor: 4.138

Review 7. Highlighting the role of Ras and Rap during Dictyostelium chemotaxis.

Authors: Arjan Kortholt; Peter J M van Haastert
Journal: Cell Signal Date: 2008-04-01 Impact factor: 4.315

Review 8. How human leukocytes track down and destroy pathogens: lessons learned from the model organism Dictyostelium discoideum.

Authors: Tian Jin; Xuehua Xu; Jun Fang; Nilgun Isik; Jianshe Yan; Joseph A Brzostowski; Dale Hereld
Journal: Immunol Res Date: 2009 Impact factor: 2.829

9. RIAM activates integrins by linking talin to ras GTPase membrane-targeting sequences.

Authors: Ho-Sup Lee; Chinten James Lim; Wilma Puzon-McLaughlin; Sanford J Shattil; Mark H Ginsberg
Journal: J Biol Chem Date: 2008-12-19 Impact factor: 5.157

10. Rap1 controls cell adhesion and cell motility through the regulation of myosin II.

Authors: Taeck J Jeon; Dai-Jen Lee; Sylvain Merlot; Gerald Weeks; Richard A Firtel
Journal: J Cell Biol Date: 2007-03-19 Impact factor: 10.539

13 in total

1. Role of cellular cytoskeleton in epithelial-mesenchymal transition process during cancer progression.

Authors: B O Sun; Yantian Fang; Zhenyang Li; Zongyou Chen; Jianbin Xiang
Journal: Biomed Rep Date: 2015-07-27

2. Minimal amino acids in the I/LWEQ domain required for anterior/posterior localization in Dictyostelium.

Authors: Hyeseon Kim; Dong-Yeop Shin; Taeck Joong Jeon
Journal: J Microbiol Date: 2017-01-26 Impact factor: 3.422

3. A role for the rap GTPase YlRsr1 in cellular morphogenesis and the involvement of YlRsr1 and the ras GTPase YlRas2 in bud site selection in the dimorphic yeast Yarrowia lipolytica.

Authors: Yun-Qing Li; Min Li; Xiao-Feng Zhao; Xiang-Dong Gao
Journal: Eukaryot Cell Date: 2014-03-07

4. Rap1 Negatively Regulates the Hippo Pathway to Polarize Directional Protrusions in Collective Cell Migration.

Authors: Yu-Chiuan Chang; Jhen-Wei Wu; Yi-Chi Hsieh; Tzu-Han Huang; Zih-Min Liao; Yi-Shan Huang; James A Mondo; Denise Montell; Anna C-C Jang
Journal: Cell Rep Date: 2018-02-20 Impact factor: 9.423

5. SILAC-based proteomic quantification of chemoattractant-induced cytoskeleton dynamics on a second to minute timescale.

Authors: Grzegorz J Sobczyk; Jun Wang; Cornelis J Weijer
Journal: Nat Commun Date: 2014-02-26 Impact factor: 14.919

6. The I/LWEQ domain in RapGAP3 required for posterior localization in migrating cells.

Authors: Mi-Rae Lee; Hyeseon Kim; Taeck J Jeon
Journal: Mol Cells Date: 2014-03-06 Impact factor: 5.034

7. Rap1-dependent pathways coordinate cytokinesis in Dictyostelium.

Authors: Katarzyna Plak; Ineke Keizer-Gunnink; Peter J M van Haastert; Arjan Kortholt
Journal: Mol Biol Cell Date: 2014-10-08 Impact factor: 4.138

8. Metadherin regulates actin cytoskeletal remodeling and enhances human gastric cancer metastasis via epithelial-mesenchymal transition.

Authors: Yaqiong Du; Bojian Jiang; Shuzheng Song; Guoqing Pei; Xiaochun Ni; Jugang Wu; Shoulian Wang; Zhengyuan Wang; Jiwei Yu
Journal: Int J Oncol Date: 2017-05-17 Impact factor: 5.650

9. Identification of the protein kinases Pyk3 and Phg2 as regulators of the STATc-mediated response to hyperosmolarity.

Authors: Linh Hai Vu; Tsuyoshi Araki; Jianbo Na; Christoph S Clemen; Jeffrey G Williams; Ludwig Eichinger
Journal: PLoS One Date: 2014-02-25 Impact factor: 3.240

10. CBP7 Interferes with the Multicellular Development of Dictyostelium Cells by Inhibiting Chemoattractant-Mediated Cell Aggregation.

Authors: Byeonggyu Park; Dong-Yeop Shin; Taeck Joong Jeon
Journal: Mol Cells Date: 2018-01-29 Impact factor: 5.034