Literature DB >> 22920651

Synthesis of tri-O-acetyl-D-allal from levoglucosenone.

Enrique D V Giordano1, Agustina Frinchaboy, Alejandra G Suárez, Rolando A Spanevello.   

Abstract

Tri-O-acetyl-D-allal has been enantiospecifically synthesized in six steps from levoglucosenone in 55% overall yield. A key step in the synthesis is the anhydro bridge ring-opening with concomitant formation of a 1,3-oxathiolane-2-thione ring.

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Year:  2012        PMID: 22920651     DOI: 10.1021/ol302061a

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  1 in total

Review 1.  Levoglucosenone: Bio-Based Platform for Drug Discovery.

Authors:  Jason E Camp; Ben W Greatrex
Journal:  Front Chem       Date:  2022-05-31       Impact factor: 5.545

  1 in total

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