Literature DB >> 2291972

[Implantation of embryonic neocortex and spinal cord into injured peripheral nerve of adult rats].

E I Chumasov, E S Petrova.   

Abstract

Spinal cord and cerebral cortex of 14-day-old embryos of Wistar rats were implanted into the sciatic nerve of mature rats in order to study dynamics of the development of neuronal and neuroglial elements in ectopic sites. By means of light and electron microscopy it has been stated that the implanted nerve cells of the cortex and spinal cord survive during 5 month and differentiate from neuroepithelial cells and neuroblasts up to young and mature neurons. It was found that thirty days after operation the spinal cord implants contained myelinated nerve fibers and numerous synapses. The data obtained suggest that the implants of fetal spinal cord are more favorable for regeneration of the injured nervous stems than the cerebral cortex.

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Year:  1990        PMID: 2291972

Source DB:  PubMed          Journal:  Biull Eksp Biol Med        ISSN: 0365-9615


  3 in total

Review 1.  Studies of histogenetic and neurodegenerative processes in the nervous system using heterotopic neurotransplantation.

Authors:  E S Petrova
Journal:  Neurosci Behav Physiol       Date:  2010-08-03

2.  Comparative morphological study of homo- and heterotopic neural transplants.

Authors:  V A Otellin; E S Petrova
Journal:  Neurosci Behav Physiol       Date:  1997 Mar-Apr

Review 3.  The Pivotal Immunoregulatory Functions of Microglia and Macrophages in Glioma Pathogenesis and Therapy.

Authors:  Seidu A Richard
Journal:  J Oncol       Date:  2022-04-04       Impact factor: 4.375

  3 in total

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