Sir,It was interesting to read a case report of Tuberculosis brain abscess and subdural empyema in an immune-competent child: Significance of AFB staining in aspirated pus by B Vijaykumar et al.[1] The treatment of childhood CNS tuberculosis is by four drugs (isoniazid, rifampicin, pyrazinamide, and ethambutol or streptomysin) along with steroids as per the Working Group on Tuberculosis, Indian Academy of Paediatrics. Consensus statement on childhood tuberculosis 2010.[2] It was not clear why did the authors used five anti-tubercular drugs in the management the case in the report. Rajneti Prasad et al, reported the use of four drugs (isoniazid, rifampicin, pyrazinamide, and ethambutol) in a child with tubercular abscess of Pons with quadriparesis.[3] Furthermore the need of evaluating the child in the case report for T cell immune-deficiency is not stressed and child needs follow up for neurological deficits and other symptoms before we assume the child is a immune-competent.