Literature DB >> 22918582

MCM structure and mechanics: what we have learned from archaeal MCM.

Ian M Slaymaker1, Xiaojiang S Chen.   

Abstract

Minichromosome maintenance (MCM) complexes have been identified as the primary replicative helicases responsible for unwinding DNA for genome replication. The focus of this chapter is to discuss the current structural and functional understanding of MCMs and their role at origins of replication, which are based mostly on the studies of MCM proteins and MCM complexes from archaeal genomes.

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Year:  2012        PMID: 22918582     DOI: 10.1007/978-94-007-4572-8_6

Source DB:  PubMed          Journal:  Subcell Biochem        ISSN: 0306-0225


  17 in total

1.  Structure of the eukaryotic MCM complex at 3.8 Å.

Authors:  Ningning Li; Yuanliang Zhai; Yixiao Zhang; Wanqiu Li; Maojun Yang; Jianlin Lei; Bik-Kwoon Tye; Ning Gao
Journal:  Nature       Date:  2015-07-29       Impact factor: 49.962

Review 2.  Structure and evolutionary origins of the CMG complex.

Authors:  Silvia Onesti; Stuart A MacNeill
Journal:  Chromosoma       Date:  2013-02-15       Impact factor: 4.316

Review 3.  Unwinding 20 Years of the Archaeal Minichromosome Maintenance Helicase.

Authors:  Lori M Kelman; William B O'Dell; Zvi Kelman
Journal:  J Bacteriol       Date:  2020-02-25       Impact factor: 3.490

Review 4.  Architecture of the Saccharomyces cerevisiae Replisome.

Authors:  Lin Bai; Zuanning Yuan; Jingchuan Sun; Roxana Georgescu; Michael E O'Donnell; Huilin Li
Journal:  Adv Exp Med Biol       Date:  2017       Impact factor: 2.622

5.  Structure and regulatory role of the C-terminal winged helix domain of the archaeal minichromosome maintenance complex.

Authors:  Christoph Wiedemann; Anna Szambowska; Sabine Häfner; Oliver Ohlenschläger; Karl-Heinz Gührs; Matthias Görlach
Journal:  Nucleic Acids Res       Date:  2015-02-20       Impact factor: 16.971

6.  Time dynamics of protein complexes in the AD11 transgenic mouse model for Alzheimer's disease like pathology.

Authors:  Ivan Arisi; Mara D'Onofrio; Rossella Brandi; Antonino Cattaneo; Paola Bertolazzi; Fabio Cumbo; Giovanni Felici; Concettina Guerra
Journal:  BMC Neurosci       Date:  2015-04-29       Impact factor: 3.288

7.  Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation.

Authors:  Zuanning Yuan; Lin Bai; Jingchuan Sun; Roxana Georgescu; Jun Liu; Michael E O'Donnell; Huilin Li
Journal:  Nat Struct Mol Biol       Date:  2016-02-08       Impact factor: 15.369

8.  Cdc6 ATPase activity disengages Cdc6 from the pre-replicative complex to promote DNA replication.

Authors:  FuJung Chang; Alberto Riera; Cecile Evrin; Jingchuan Sun; Huilin Li; Christian Speck; Michael Weinreich
Journal:  Elife       Date:  2015-08-25       Impact factor: 8.140

9.  Functional conservation of the pre-sensor one beta-finger hairpin (PS1-hp) structures in mini-chromosome maintenance proteins of Saccharomyces cerevisiae and archaea.

Authors:  Christopher J Ramey; Robert A Sclafani
Journal:  G3 (Bethesda)       Date:  2014-05-28       Impact factor: 3.154

10.  The haloarchaeal MCM proteins: bioinformatic analysis and targeted mutagenesis of the β7-β8 and β9-β10 hairpin loops and conserved zinc binding domain cysteines.

Authors:  Tatjana P Kristensen; Reeja Maria Cherian; Fiona C Gray; Stuart A MacNeill
Journal:  Front Microbiol       Date:  2014-03-26       Impact factor: 5.640

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