Literature DB >> 2291733

Torsade de pointes associated with perhexiline maleate therapy.

G D Kerr1, G Ingham.   

Abstract

Multiform ventricular tachycardia (torsade de pointes) is a recognised proarrhythmic effect of drugs which prolong the QT interval. A case is now described for the first time where torsade de pointes occurred with the administration of the anti-anginal agent perhexiline maleate.

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Year:  1990        PMID： 2291733     DOI： 10.1111/j.1445-5994.1990.tb00431.x

Source DB:  PubMed          Journal:  Aust N Z J Med        ISSN： 0004-8291


  3 in total

1.  Inhibition of HERG channels stably expressed in a mammalian cell line by the antianginal agent perhexiline maleate.

Authors:  B D Walker; S M Valenzuela; C B Singleton; H Tie; J A Bursill; K R Wyse; M R Qiu; S N Breit; T J Campbell
Journal:  Br J Pharmacol       Date:  1999-05       Impact factor: 8.739

2.  Terodiline causes polymorphic ventricular tachycardia due to reduced heart rate and prolongation of QT interval.

Authors:  D A Stewart; J Taylor; S Ghosh; G J Macphee; I Abdullah; J M McLenachan; D J Stott
Journal:  Eur J Clin Pharmacol       Date:  1992       Impact factor: 2.953

Review 3.  Withdrawal of prenylamine: perspectives on pharmacological, clinical and regulatory outcomes following the first QT-related casualty.

Authors:  Rashmi R Shah; Peter D Stonier
Journal:  Ther Adv Drug Saf       Date:  2018-06-18
  3 in total

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