Literature DB >> 2291673

Effect of oral antacid administration on the pharmacokinetics of oral fluconazole.

J E Thorpe1, N Baker, M Bromet-Petit.   

Abstract

Absorption and elimination of fluconazole after oral administration of a 100-mg capsule were unaffected by concomitant administration of an antacid containing aluminum and magnesium hydroxides.

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Year:  1990        PMID： 2291673      PMCID： PMC171987          DOI： 10.1128/AAC.34.10.2032

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  7 in total

1.  Gas chromatographic method for the determination of fluconazole, a novel antifungal agent, in human plasma and urine.

Authors:  P R Wood; M H Tarbit
Journal:  J Chromatogr       Date:  1986-11-28

2.  The two-period cross-over clinical trial.

Authors:  M Hills; P Armitage
Journal:  Br J Clin Pharmacol       Date:  1979-07       Impact factor: 4.335

3.  Gastric secretory failure in patients with the acquired immunodeficiency syndrome (AIDS).

Authors:  G Lake-Bakaar; E Quadros; S Beidas; M Elsakr; W Tom; D E Wilson; H P Dincsoy; P Cohen; E W Straus
Journal:  Ann Intern Med       Date:  1988-09-15       Impact factor: 25.391

4.  Single-dose oral fluconazole in the treatment of vaginal candidosis.

Authors:  K W Brammer; J M Feczko
Journal:  Ann N Y Acad Sci       Date:  1988       Impact factor: 5.691

5.  The influence of gastric acidity on the bio-availability of ketoconazole.

Authors:  J W Van Der Meer; J J Keuning; H W Scheijgrond; J Heykants; J Van Cutsem; J Brugmans
Journal:  J Antimicrob Chemother       Date:  1980-07       Impact factor: 5.790

6.  Gastropathy and ketoconazole malabsorption in the acquired immunodeficiency syndrome (AIDS).

Authors:  G Lake-Bakaar; W Tom; D Lake-Bakaar; N Gupta; S Beidas; M Elsakr; E Straus
Journal:  Ann Intern Med       Date:  1988-09-15       Impact factor: 25.391

7.  Fluconazole in the management of oropharyngeal candidosis in a predominantly HIV antibody-positive group of patients.

Authors:  B Dupont; E Drouhet
Journal:  J Med Vet Mycol       Date:  1988-02
  7 in total
  10 in total

1.  Clinical pharmacokinetics of fluconazole in superficial and systemic mycoses.

Authors:  D Debruyne
Journal:  Clin Pharmacokinet       Date:  1997-07       Impact factor: 6.447

Review 2.  Clinically significant drug interactions with antacids: an update.

Authors:  Ryuichi Ogawa; Hirotoshi Echizen
Journal:  Drugs       Date:  2011-10-01       Impact factor: 9.546

3.  Pharmacokinetics of oral fluconazole when used for prophylaxis in bone marrow transplant recipients.

Authors:  A El-Yazigi; M Ellis; P Ernst; D Spence; R Hussain; F J Baillie
Journal:  Antimicrob Agents Chemother       Date:  1997-05       Impact factor: 5.191

Review 4.  Systemic antifungal agents. Drug interactions of clinical significance.

Authors:  E Albengres; H Le Louët; J P Tillement
Journal:  Drug Saf       Date:  1998-02       Impact factor: 5.606

Review 5.  Fluconazole. An update of its antimicrobial activity, pharmacokinetic properties, and therapeutic use in vaginal candidiasis.

Authors:  C M Perry; R Whittington; D McTavish
Journal:  Drugs       Date:  1995-06       Impact factor: 9.546

Review 6.  Clinical pharmacokinetics of fluconazole.

Authors:  D Debruyne; J P Ryckelynck
Journal:  Clin Pharmacokinet       Date:  1993-01       Impact factor: 6.447

Review 7.  Drug interactions with antacids. Mechanisms and clinical significance.

Authors:  D C Sadowski
Journal:  Drug Saf       Date:  1994-12       Impact factor: 5.606

Review 8.  Fluconazole. An update of its pharmacodynamic and pharmacokinetic properties and therapeutic use in major superficial and systemic mycoses in immunocompromised patients.

Authors:  K L Goa; L B Barradell
Journal:  Drugs       Date:  1995-10       Impact factor: 9.546

9.  Determination and characterization of metronidazole-kaolin interaction.

Authors:  Fadilah Sfouq Aleanizy; Fulwah Alqahtani; Omaimah Al Gohary; Eram El Tahir; Rania Al Shalabi
Journal:  Saudi Pharm J       Date:  2014-07-08       Impact factor: 4.330

10.  Developmental changes of fluconazole clearance in neonates and infants in relation to ontogeny of glomerular filtration rate: literature review and data analysis.

Authors:  Kazutoshi Murakoso; Ryoichi Minagawa; Hirotoshi Echizen
Journal:  J Pharm Health Care Sci       Date:  2018-03-20
  10 in total

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