Literature DB >> 22915821

The assembly domain of the small capsid protein of Kaposi's sarcoma-associated herpesvirus.

Dale Kreitler1, Christopher M Capuano, Brandon W Henson, Erin N Pryce, Daniel Anacker, J Michael McCaffery, Prashant J Desai.   

Abstract

Self-assembly of Kaposi's sarcoma-associated herpesvirus capsids occurs when six proteins are coexpressed in insect cells using recombinant baculoviruses; however, if the small capsid protein (SCP) is omitted from the coinfection, assembly does not occur. Herein we delineate and identify precisely the assembly domain and the residues of SCP required for assembly. Hence, six residues, R14, D18, V25, R46, G66, and R70 in the assembly domain, when changed to alanine, completely abolish or reduce capsid assembly.

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Year:  2012        PMID： 22915821      PMCID： PMC3486306          DOI： 10.1128/JVI.01430-12

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  19 in total

1.  Capsid assembly and DNA packaging in herpes simplex virus.

Authors: 
Journal:  Rev Med Virol       Date:  1997-07       Impact factor: 6.989

2.  Lytic replication of Kaposi's sarcoma-associated herpesvirus results in the formation of multiple capsid species: isolation and molecular characterization of A, B, and C capsids from a gammaherpesvirus.

Authors:  K Nealon; W W Newcomb; T R Pray; C S Craik; J C Brown; D H Kedes
Journal:  J Virol       Date:  2001-03       Impact factor: 5.103

3.  A domain in the herpes simplex virus 1 triplex protein VP23 is essential for closure of capsid shells into icosahedral structures.

Authors:  Hong Seok Kim; Eugene Huang; Jigisha Desai; Marieta Sole; Erin N Pryce; Mercy E Okoye; Stanley Person; Prashant J Desai
Journal:  J Virol       Date:  2011-09-28       Impact factor: 5.103

4.  The amino-conserved domain of human cytomegalovirus UL80a proteins is required for key interactions during early stages of capsid formation and virus production.

Authors:  Amy N Loveland; Nang L Nguyen; Edward J Brignole; Wade Gibson
Journal:  J Virol       Date:  2006-11-01       Impact factor: 5.103

5.  Functional analysis of the triplex proteins (VP19C and VP23) of herpes simplex virus type 1.

Authors:  Mercy E Okoye; Gerry L Sexton; Eugene Huang; J Michael McCaffery; Prashant Desai
Journal:  J Virol       Date:  2006-01       Impact factor: 5.103

6.  Three-dimensional structure of the Epstein-Barr virus capsid.

Authors:  Raphaele Germi; Gregory Effantin; Laurence Grossi; Rob W H Ruigrok; Patrice Morand; Guy Schoehn
Journal:  J Gen Virol       Date:  2012-05-16       Impact factor: 3.891

7.  Reconstitution of the Kaposi's sarcoma-associated herpesvirus nuclear egress complex and formation of nuclear membrane vesicles by coexpression of ORF67 and ORF69 gene products.

Authors:  Prashant J Desai; Erin N Pryce; Brandon W Henson; Eric M Luitweiler; Jonathan Cothran
Journal:  J Virol       Date:  2011-10-19       Impact factor: 5.103

8.  Functional characterization of Kaposi's sarcoma-associated herpesvirus small capsid protein by bacterial artificial chromosome-based mutagenesis.

Authors:  Narayanan Sathish; Yan Yuan
Journal:  Virology       Date:  2010-09-20       Impact factor: 3.616

9.  Molecular interactions of Epstein-Barr virus capsid proteins.

Authors:  Wen-Hung Wang; Li-Kwan Chang; Shih-Tung Liu
Journal:  J Virol       Date:  2010-12-08       Impact factor: 5.103

10.  Small capsid protein pORF65 is essential for assembly of Kaposi's sarcoma-associated herpesvirus capsids.

Authors:  Edward M Perkins; Daniel Anacker; Aaron Davis; Vishwam Sankar; Richard F Ambinder; Prashant Desai
Journal:  J Virol       Date:  2008-05-07       Impact factor: 5.103
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  2 in total

1.  CryoEM and mutagenesis reveal that the smallest capsid protein cements and stabilizes Kaposi's sarcoma-associated herpesvirus capsid.

Authors:  Xinghong Dai; Danyang Gong; Yuchen Xiao; Ting-Ting Wu; Ren Sun; Z Hong Zhou
Journal:  Proc Natl Acad Sci U S A       Date:  2015-02-02       Impact factor: 11.205

2.  A hydrophobic domain within the small capsid protein of Kaposi's sarcoma-associated herpesvirus is required for assembly.

Authors:  Christopher M Capuano; Peter Grzesik; Dale Kreitler; Erin N Pryce; Keshal V Desai; Gavin Coombs; J Michael McCaffery; Prashant J Desai
Journal:  J Gen Virol       Date:  2014-05-13       Impact factor: 3.891
  2 in total

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