| Literature DB >> 2291396 |
G V Martino1, L M Grimaldi, D M Franciotta, G Piccolo, R Brustia, L Minali, G V Melzi d'Eril.
Abstract
We report a case of herpetic brainstem encephalitis (HBE) retrospectively diagnosed in adult patient. Conventional immunovirological studies failed to disclose the etiology of this patient's affection. An isoelectric focusing-antigen overlay (IEF-O) technique showed that the target of one of the four cerebrospinal fluid oligoclonal bands was herpes simplex virus (HSV)-1 glycoprotein B, indicating a specific anti-HSV immunoresponse restricted to the CNS. IEF-O may represent a useful support for in vivo diagnosis of HBE.Entities:
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Year: 1990 PMID： 2291396 DOI： 10.1111/j.1600-0404.1990.tb03318.x
Source DB: PubMed Journal: Acta Neurol Scand ISSN： 0001-6314 Impact factor: 3.209