Literature DB >> 22913619

Greater cognitive deterioration in women than men with Alzheimer's disease: a meta analysis.

Karen Irvine1, Keith R Laws, Tim M Gale, Tejinder K Kondel.   

Abstract

Studies reporting on the cognitive abilities of men and women with Alzheimer's disease (AD) are surprisingly rare. We carried out a meta-analysis of neurocognitive data from 15 studies (n = 828 men; 1,238 women), which revealed a consistent male advantage on verbal and visuospatial tasks and tests of episodic and semantic memory. Moderator regression analyses showed that age, education level, and dementia severity did not significantly predict the male advantage. Reasons posited for this advantage include a reduction of estrogen in postmenopausal women, sex differences in AD pathology, and greater cognitive reserve in men.

Entities:  

Mesh：

Year:  2012        PMID： 22913619     DOI： 10.1080/13803395.2012.712676

Source DB:  PubMed          Journal:  J Clin Exp Neuropsychol        ISSN： 1380-3395            Impact factor:   2.475


  68 in total

1.  Sex differences in the development of mild cognitive impairment and probable Alzheimer's disease as predicted by hippocampal volume or white matter hyperintensities.

Authors:  Shanna L Burke; Tianyan Hu; Nicole M Fava; Tan Li; Miriam J Rodriguez; Katie L Schuldiner; Aaron Burgess; Angela Laird
Journal:  J Women Aging       Date:  2018-01-10

Review 2.  Sex differences in cognitive impairment in Alzheimer's disease.

Authors:  Keith R Laws; Karen Irvine; Tim M Gale
Journal:  World J Psychiatry       Date:  2016-03-22

Review 3.  Sex differences in neurodevelopmental and neurodegenerative disorders: Focus on microglial function and neuroinflammation during development.

Authors:  Richa Hanamsagar; Staci D Bilbo
Journal:  J Steroid Biochem Mol Biol       Date:  2015-10-23       Impact factor: 4.292

Review 4.  Sex and the development of Alzheimer's disease.

Authors:  Christian J Pike
Journal:  J Neurosci Res       Date:  2017-01-02       Impact factor: 4.164

5.  An exploratory investigation of brain-selective estrogen treatment in males using a mouse model of Alzheimer's disease.

Authors:  Anna E Tschiffely; Rosemary A Schuh; Katalin Prokai-Tatrai; Mary Ann Ottinger; Laszlo Prokai
Journal:  Horm Behav       Date:  2017-12-22       Impact factor: 3.587

Review 6.  Sexual dimorphism in predisposition to Alzheimer's disease.

Authors:  Daniel W Fisher; David A Bennett; Hongxin Dong
Journal:  Neurobiol Aging       Date:  2018-04-17       Impact factor: 4.673

Review 7.  Sex differences in cognitive impairment and Alzheimer's disease.

Authors:  Rena Li; Meharvan Singh
Journal:  Front Neuroendocrinol       Date:  2014-01-13       Impact factor: 8.606

Review 8.  Understanding the impact of sex and gender in Alzheimer's disease: A call to action.

Authors:  Rebecca A Nebel; Neelum T Aggarwal; Lisa L Barnes; Aimee Gallagher; Jill M Goldstein; Kejal Kantarci; Monica P Mallampalli; Elizabeth C Mormino; Laura Scott; Wai Haung Yu; Pauline M Maki; Michelle M Mielke
Journal:  Alzheimers Dement       Date:  2018-06-12       Impact factor: 21.566

9.  Development of a data-mining algorithm to identify ages at reproductive milestones in electronic medical records.

Authors:  Jennifer Malinowski; Eric Farber-Eger; Dana C Crawford
Journal:  Pac Symp Biocomput       Date:  2014

10.  Greater memory impairment in dementing females than males relative to sex-matched healthy controls.

Authors:  Shawn D Gale; Leslie Baxter; Juliann Thompson
Journal:  J Clin Exp Neuropsychol       Date:  2016-01-06       Impact factor: 2.475
View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.