INTRODUCTION AND HYPOTHESIS: Outcomes of xenografts in incontinence surgery are uncommon. Our objective was to report long-term outcomes of women after porcine dermis (PD) bladder neck sling. METHODS: Seventy women completed a mean follow-up of 62.1 months. "Global cure" equaled SEAPI subjective composite = 0 and visual analog score ≥8. "Stress urinary incontinence (SUI) cure" equaled SEAPI-subjective (S) subset = 0 and negative cough stress test. RESULTS: The SUI cure rate was 42.9 % and global cure rate was 11.4 %. Perioperative complications were seen in <10 % of women. The mean time to SUI recurrence was 10.4 months, with 30 of 40 women redeveloping SUI <12 months after sling. Twenty women (28.6 %) have since undergone additional anti-incontinence procedures. There was a significant postoperative improvement in SEAPI scores, daily pad use, and quality of life (QOL) indices. CONCLUSIONS: At long-term follow-up, PD is not a durable material in sling surgery. Although QOL generally improves after surgery, most SUI recurrences occurred soon after surgery.
INTRODUCTION AND HYPOTHESIS: Outcomes of xenografts in incontinence surgery are uncommon. Our objective was to report long-term outcomes of women after porcine dermis (PD) bladder neck sling. METHODS: Seventy women completed a mean follow-up of 62.1 months. "Global cure" equaled SEAPI subjective composite = 0 and visual analog score ≥8. "Stress urinary incontinence (SUI) cure" equaled SEAPI-subjective (S) subset = 0 and negative cough stress test. RESULTS: The SUI cure rate was 42.9 % and global cure rate was 11.4 %. Perioperative complications were seen in <10 % of women. The mean time to SUI recurrence was 10.4 months, with 30 of 40 women redeveloping SUI <12 months after sling. Twenty women (28.6 %) have since undergone additional anti-incontinence procedures. There was a significant postoperative improvement in SEAPI scores, daily pad use, and quality of life (QOL) indices. CONCLUSIONS: At long-term follow-up, PD is not a durable material in sling surgery. Although QOL generally improves after surgery, most SUI recurrences occurred soon after surgery.
Authors: Daniel M Morgan; Rodney L Dunn; Dee E Fenner; Gary Faerber; John O L DeLancey; Edward J McGuire; John T Wei Journal: J Urol Date: 2007-02 Impact factor: 7.450
Authors: Alex Gomelsky; Rashel M Haverkorn; Walter J Simoneaux; Seth Bilello; William S Kubricht Journal: Int Urogynecol J Pelvic Floor Dysfunct Date: 2007-03-01
Authors: Anthony J Woodruff; Emily E Cole; Roger R Dmochowski; Harriette M Scarpero; Edwin N Beckman; J Christian Winters Journal: Urology Date: 2008-05-05 Impact factor: 2.649