Literature DB >> 22907604

[Intraoperative frozen section diagnosis of head and neck tumors: possibilities, limitations, pitfalls and tips for the daily practice].

A Agaimy1, F Stelzle, J Zenk, H Iro.   

Abstract

Intraoperative consultation (synonym: frozen section diagnostics) has increasingly gained significance for the daily practice in head and neck surgery. The main aim of this investigation method which is usually associated with much stress and effort is to facilitate an optimal and timely oncological surgical treatment of neoplastic diseases with a minimum rate of postoperative functional disturbance. In order to achieve this purpose pathologists are expected to deliver as much correct information as possible to accurately influence intraoperative surgical decisions. At the same time this aim should be reached without significantly and unnecessarily increasing the workload for the pathology laboratory and without significantly inducing tissue artifacts. This would otherwise negatively influence the tissue quality for permanent section examination and consequently the overall quality of diagnosis and tumor staging. Thus, the quality and efficacy of frozen sections span a spectrum with the highest quality having the least possible false negative rate on the one hand and a false positive result of approximately zero on the other hand. Sticking to this approach would result in a high positive impact on the surgical treatment of a variety of neoplastic diseases and help to minimize or even eliminate the rate of medicolegal consequences.

Entities:  

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Year:  2012        PMID: 22907604     DOI: 10.1007/s00292-012-1598-4

Source DB:  PubMed          Journal:  Pathologe        ISSN: 0172-8113            Impact factor:   1.011


  18 in total

1.  Frozen section during parotid surgery revisited: efficacy of its applications and changing trend of indications.

Authors:  David Sau Yan Wong
Journal:  Head Neck       Date:  2002-02       Impact factor: 3.147

2.  Oral squamous cell carcinoma with mandibular bone invasion: intraoperative evaluation of bone margins by routine frozen section.

Authors:  Elizabeth A Bilodeau; Simion Chiosea
Journal:  Head Neck Pathol       Date:  2011-04-22

3.  Utility of frozen section in assessment of margins and neck node metastases in patients undergoing surgery for carcinoma of the tongue.

Authors:  Pankaj Chaturvedi; Bikramjit Singh; Sudhir Nair; Deepa Nair; Shubhada V Kane; Anil D'cruz; Sourav Datta; Prashant Pawar; Sagar Vaishampayan
Journal:  J Cancer Res Ther       Date:  2012-01       Impact factor: 1.805

4.  Prognostic importance of "clear versus revised margins" in oral and pharyngeal cancer.

Authors:  Pingling Kwok; Otto Gleich; Gerhard Hübner; Jürgen Strutz
Journal:  Head Neck       Date:  2010-11       Impact factor: 3.147

5.  Intraoperative consultation/final diagnosis correlation: relationship to tissue type and pathologic process.

Authors:  Valerie A White; Martin J Trotter
Journal:  Arch Pathol Lab Med       Date:  2008-01       Impact factor: 5.534

6.  Supraomohyoid neck dissection with frozen section biopsy as a staging procedure in the clinically node-negative neck in carcinoma of the oral cavity.

Authors:  J J Manni; F J van den Hoogen
Journal:  Am J Surg       Date:  1991-10       Impact factor: 2.565

7.  Accuracy of intraoperative staging of the NO neck in squamous cell carcinoma.

Authors:  C H Rassekh; J T Johnson; E N Myers
Journal:  Laryngoscope       Date:  1995-12       Impact factor: 3.325

8.  Parotidectomy: a ten year experience with fine needle aspiration and frozen section biopsy correlation.

Authors:  C A Megerian; A J Maniglia
Journal:  Ear Nose Throat J       Date:  1994-06       Impact factor: 1.697

9.  The value of frozen section analysis of the sentinel lymph node in clinically N0 squamous cell carcinoma of the oral cavity and oropharynx.

Authors:  Laurent Tschopp; Michel Nuyens; Edouard Stauffer; Thomas Krause; Peter Zbären
Journal:  Otolaryngol Head Neck Surg       Date:  2005-01       Impact factor: 3.497

10.  Accuracy of fine needle aspiration cytology and frozen section histopathology for lesions of the major salivary glands.

Authors:  Lincoln G L Tan; Mark L C Khoo
Journal:  Ann Acad Med Singapore       Date:  2006-04       Impact factor: 2.473

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