Literature DB >> 22907483

Expedited partner therapy for sexually transmitted infections.

Matthew Hogben1, Sarah Kidd, Gale R Burstein.   

Abstract

PURPOSE OF REVIEW: In 2006, the Centers for Disease Control and Prevention recommended Expedited Partner Therapy (EPT) as a clinical option for assuring treatment of sex partners of persons infected with sexually transmitted infections. In this review, we provide an update on research, evaluation and efforts to increase EPT coverage. We also attend to EPT for gonorrhea in the context of antimicrobial resistance. RECENT
FINDINGS: Controlled trials in the United States and United Kingdom have presented increasing variety in intervention approaches. Trials and program evaluations typically demonstrate increased partner treatment rates, although only some studies show reductions in follow-up infection rates. Coverage has increased substantially, with over 30 states permitting EPT for chlamydial infection, gonorrhea, or both. The prospect of cephalosporin-resistant gonorrhea, however, raises the prospect that EPT may become less feasible as a partner treatment approach for gonorrhea patients.
SUMMARY: Clinicians should continue to be aware of the importance of partner managements for STD-infected patients, with EPT being an evidence-based intervention in that respect. The variety in EPT models provides alternatives that may suit some practices and venues. For clinicians seeing gonorrhea patients, effective counseling models - enhanced patient referral - should be closely examined in case oral treatment for gonorrhea becomes infeasible.

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Year:  2012        PMID: 22907483      PMCID: PMC6357222          DOI: 10.1097/GCO.0b013e3283577e9d

Source DB:  PubMed          Journal:  Curr Opin Obstet Gynecol        ISSN: 1040-872X            Impact factor:   1.927


  40 in total

1.  Remarkable increase in central Japan in 2001-2002 of Neisseria gonorrhoeae isolates with decreased susceptibility to penicillin, tetracycline, oral cephalosporins, and fluoroquinolones.

Authors:  Masayasu Ito; Mitsuru Yasuda; Shigeaki Yokoi; Shin-ichi Ito; Yoshito Takahashi; Satoshi Ishihara; Shin-ichi Maeda; Takashi Deguchi
Journal:  Antimicrob Agents Chemother       Date:  2004-08       Impact factor: 5.191

2.  Effect of expedited treatment of sex partners on recurrent or persistent gonorrhea or chlamydial infection.

Authors:  Matthew R Golden; William L H Whittington; H Hunter Handsfield; James P Hughes; Walter E Stamm; Matthew Hogben; Agnes Clark; Cheryl Malinski; Jennifer R L Helmers; Katherine K Thomas; King K Holmes
Journal:  N Engl J Med       Date:  2005-02-17       Impact factor: 91.245

3.  Treatment of uncomplicated gonococcal urethritis by double-dosing of 200 mg cefixime at a 6-h interval.

Authors:  Takashi Deguchi; Mitsuru Yasuda; Shigeaki Yokoi; Ken-Ichiro Ishida; Masayasu Ito; Satoshi Ishihara; Ken Minamidate; Yoshimasa Harada; Kanhin Tei; Kentaro Kojima; Masayoshi Tamaki; Shin-Ichi Maeda
Journal:  J Infect Chemother       Date:  2003-03       Impact factor: 2.211

4.  Patient-delivered partner treatment for male urethritis: a randomized, controlled trial.

Authors:  Patricia Kissinger; Hamish Mohammed; Gwangi Richardson-Alston; Jami S Leichliter; Stephanie N Taylor; David H Martin; Thomas A Farley
Journal:  Clin Infect Dis       Date:  2005-07-19       Impact factor: 9.079

5.  A remarkable reduction in the susceptibility of Neisseria gonorrhoeae isolates to cephems and the selection of antibiotic regimens for the single-dose treatment of gonococcal infection in Japan.

Authors:  Masatoshi Tanaka; Hiroshi Nakayama; Hiroaki Tunoe; Toshihisa Egashira; Akiko Kanayama; Takeshi Saika; Intetsu Kobayashi; Seiji Naito
Journal:  J Infect Chemother       Date:  2002-03       Impact factor: 2.211

Review 6.  Improved effectiveness of partner notification for patients with sexually transmitted infections: systematic review.

Authors:  Sven Trelle; Aijing Shang; Linda Nartey; Jackie A Cassell; Nicola Low
Journal:  BMJ       Date:  2007-02-17

7.  Field-delivered therapy increases treatment for chlamydia and gonorrhea.

Authors:  Katherine C Steiner; Veronica Davila; Charlotte K Kent; Janice K Chaw; Lyn Fischer; Jeffrey D Klausner
Journal:  Am J Public Health       Date:  2003-06       Impact factor: 9.308

8.  Surveillance of antimicrobial susceptibilities in Neisseria gonorrhoeae in Nanjing, China, 1999-2006.

Authors:  Xiaohong Su; Faxing Jiang; Xiuqing Dai; Houhua Sun; Shunzhang Ye
Journal:  Sex Transm Dis       Date:  2007-12       Impact factor: 2.830

9.  Patient-delivered partner treatment with azithromycin to prevent repeated Chlamydia trachomatis infection among women: a randomized, controlled trial.

Authors:  Julia A Schillinger; Patricia Kissinger; Helene Calvet; William L H Whittington; Ray L Ransom; Maya R Sternberg; Stuart M Berman; Charlotte K Kent; David H Martin; M Kim Oh; H Hunter Handsfield; Gail Bolan; Lauri E Markowitz; J Dennis Fortenberry
Journal:  Sex Transm Dis       Date:  2003-01       Impact factor: 2.830

10.  Threat to cefixime treatment for gonorrhea.

Authors:  Shigeaki Yokoi; Takashi Deguchi; Tomomi Ozawa; Mitsuru Yasuda; Shin-ichi Ito; Yasuaki Kubota; Masayoshi Tamaki; Shin-ichi Maeda
Journal:  Emerg Infect Dis       Date:  2007-08       Impact factor: 6.883

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