Literature DB >> 22905680

Parallel microflow photochemistry: process optimization, scale-up, and library synthesis.

Alexander Yavorskyy1, Oksana Shvydkiv, Norbert Hoffmann, Kieran Nolan, Michael Oelgemöller.   

Abstract

A novel, multimicrocapillary flow reactor (MμCFR) was constructed and applied to a series of sensitized photoadditions involving 2(5H)-furanones. The reactor allowed for rapid and energy-, time-, and space-efficient sensitizer screening, process optimization, validation, scale-up, and library synthesis.

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Year:  2012        PMID: 22905680     DOI: 10.1021/ol301773r

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  7 in total

1.  Tandem dienone photorearrangement-cycloaddition for the rapid generation of molecular complexity.

Authors:  Pieter H Bos; Mitchell T Antalek; John A Porco; Corey R J Stephenson
Journal:  J Am Chem Soc       Date:  2013-11-13       Impact factor: 15.419

2.  Combining photochemistry and catalysis: rapid access to sp3 - rich polyheterocycles from simple pyrroles.

Authors:  Emma E Blackham; Jonathan P Knowles; Jonathan Burgess; Kevin I Booker-Milburn
Journal:  Chem Sci       Date:  2016-01-04       Impact factor: 9.825

3.  A coating from nature.

Authors:  Johannes G H Hermens; Thomas Freese; Keimpe J van den Berg; Rogier van Gemert; Ben L Feringa
Journal:  Sci Adv       Date:  2020-12-16       Impact factor: 14.136

4.  Flow photochemistry: Old light through new windows.

Authors:  Jonathan P Knowles; Luke D Elliott; Kevin I Booker-Milburn
Journal:  Beilstein J Org Chem       Date:  2012-11-21       Impact factor: 2.883

5.  Multidimensional reaction screening for photochemical transformations as a tool for discovering new chemotypes.

Authors:  Véronique I Martin; John R Goodell; Oscar J Ingham; John A Porco; Aaron B Beeler
Journal:  J Org Chem       Date:  2014-04-16       Impact factor: 4.354

Review 6.  Dawn of a new era in industrial photochemistry: the scale-up of micro- and mesostructured photoreactors.

Authors:  Emine Kayahan; Mathias Jacobs; Leen Braeken; Leen Cj Thomassen; Simon Kuhn; Tom van Gerven; M Enis Leblebici
Journal:  Beilstein J Org Chem       Date:  2020-10-08       Impact factor: 2.883

Review 7.  Direct Photocatalyzed Hydrogen Atom Transfer (HAT) for Aliphatic C-H Bonds Elaboration.

Authors:  Luca Capaldo; Davide Ravelli; Maurizio Fagnoni
Journal:  Chem Rev       Date:  2021-08-06       Impact factor: 60.622

  7 in total

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