Literature DB >> 22902178

Fetuin-A function in systemic mineral metabolism.

Marietta Herrmann1, Anne Kinkeldey, Willi Jahnen-Dechent.   

Abstract

Fetuin-A is a liver-derived plasma protein involved in calcified matrix metabolism. Fetuin-A mediates the formation and stabilization of calciprotein particles (CPPs), soluble colloids made of fetuin-A, further serum proteins, and calcium phosphate mineral. CPP formation ensures mineral solubilization and rapid clearance from circulation by macrophages of the mononuclear phagocyte system, thus preventing pathological calcification. Accordingly, low levels of free serum fetuin-A and high serum CPPs are associated with pathological calcification in patients suffering from chronic kidney disease.
Copyright © 2012 Elsevier Inc. All rights reserved.

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Year:  2012        PMID: 22902178     DOI: 10.1016/j.tcm.2012.07.020

Source DB:  PubMed          Journal:  Trends Cardiovasc Med        ISSN: 1050-1738            Impact factor:   6.677


  12 in total

1.  Regulatory inhibition of biological tissue mineralization by calcium phosphate through post-nucleation shielding by fetuin-A.

Authors:  Joshua C Chang; Robert M Miura
Journal:  J Chem Phys       Date:  2016-04-21       Impact factor: 3.488

Review 2.  PXE, a Mysterious Inborn Error Clarified.

Authors:  Piet Borst; András Váradi; Koen van de Wetering
Journal:  Trends Biochem Sci       Date:  2018-11-13       Impact factor: 13.807

3.  Unified theory on the pathogenesis of Randall's plaques and plugs.

Authors:  Saeed R Khan; Benjamin K Canales
Journal:  Urolithiasis       Date:  2014-08-14       Impact factor: 3.436

4.  Regulation of macromolecular modulators of urinary stone formation by reactive oxygen species: transcriptional study in an animal model of hyperoxaluria.

Authors:  Saeed R Khan; Sunil Joshi; Wei Wang; Ammon B Peck
Journal:  Am J Physiol Renal Physiol       Date:  2014-03-05

Review 5.  Calcific uraemic arteriolopathy: a rare disease with a potentially high impact on chronic kidney disease-mineral and bone disorder.

Authors:  Vincent M Brandenburg; Smeeta Sinha; Paula Specht; Markus Ketteler
Journal:  Pediatr Nephrol       Date:  2014-01-29       Impact factor: 3.714

6.  Reactive oxygen species, inflammation and calcium oxalate nephrolithiasis.

Authors:  Saeed R Khan
Journal:  Transl Androl Urol       Date:  2014-09-01

Review 7.  Therapeutic Interference With Vascular Calcification-Lessons From Klotho-Hypomorphic Mice and Beyond.

Authors:  Florian Lang; Christina Leibrock; Lisann Pelzl; Meinrad Gawaz; Burkert Pieske; Ioana Alesutan; Jakob Voelkl
Journal:  Front Endocrinol (Lausanne)       Date:  2018-05-04       Impact factor: 5.555

8.  Transcriptional study of hyperoxaluria and calcium oxalate nephrolithiasis in male rats: Inflammatory changes are mainly associated with crystal deposition.

Authors:  Sunil Joshi; Wei Wang; Saeed R Khan
Journal:  PLoS One       Date:  2017-11-01       Impact factor: 3.240

9.  Fetuin-A-containing calciprotein particles reduce mineral stress in the macrophage.

Authors:  Edward R Smith; Eric Hanssen; Lawrence P McMahon; Stephen G Holt
Journal:  PLoS One       Date:  2013-04-08       Impact factor: 3.240

10.  Urine and serum fetuin-A levels in patients with urolithiasis.

Authors:  Rajat Arora; Nitin Abrol; B Antonisamy; S Vanitha; J Chandrasingh; Santosh Kumar; Nitin Kekre; Antony Devasia
Journal:  Indian J Urol       Date:  2017 Oct-Dec
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