Literature DB >> 22902174

[Repetitive transcranial magnetic stimulation in the treatment of obsessive-compulsive disorder].

C Nauczyciel1, D Drapier.   

Abstract

Obsessive-compulsive disorder (OCD) is a chronic, often resistant neuropsychiatric disorder leading to severe social impairment. Neurophysiological theories suggest an imbalance between the frontal-striatal circuits involved in goal directed behavior. Repetitive transcranial magnetic stimulation (rTMS) has been suggested as a therapeutic option. Various targets of stimulation have been tested based on neurophysiological theories. The first studies, stimulating the dorsolateral prefrontal cortex, did not show an efficacy but the more recent ones, stimulating the supplementary motor area or the orbitofrontal cortex, seem to be promising. Further studies with larger sample should be conducted in order to propose rTMS as a therapeutic tool for OCD.
Copyright © 2012 Elsevier Masson SAS. All rights reserved.

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Year:  2012        PMID: 22902174     DOI: 10.1016/j.neurol.2012.05.006

Source DB:  PubMed          Journal:  Rev Neurol (Paris)        ISSN: 0035-3787            Impact factor:   2.607


  2 in total

Review 1.  Targeting Neural Endophenotypes of Eating Disorders with Non-invasive Brain Stimulation.

Authors:  Katharine A Dunlop; Blake Woodside; Jonathan Downar
Journal:  Front Neurosci       Date:  2016-02-16       Impact factor: 4.677

2.  A pilot trial of repetitive transcranial magnetic stimulation of the dorsomedial prefrontal cortex in anorexia nervosa: resting fMRI correlates of response.

Authors:  D Blake Woodside; Katharine Dunlop; Charlene Sathi; Eileen Lam; Brigitte McDonald; Jonathan Downar
Journal:  J Eat Disord       Date:  2021-04-17
  2 in total

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